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405 results

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Page 1
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE. Canver MC, et al. Among authors: smith ec. Nature. 2015 Nov 12;527(7577):192-7. doi: 10.1038/nature15521. Epub 2015 Sep 16. Nature. 2015. PMID: 26375006 Free PMC article.
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH. Bauer DE, et al. Among authors: smith ec. Science. 2013 Oct 11;342(6155):253-7. doi: 10.1126/science.1242088. Science. 2013. PMID: 24115442 Free PMC article.
Strict in vivo specificity of the Bcl11a erythroid enhancer.
Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH. Smith EC, et al. Blood. 2016 Nov 10;128(19):2338-2342. doi: 10.1182/blood-2016-08-736249. Epub 2016 Oct 5. Blood. 2016. PMID: 27707736 Free PMC article.
Chronic Myelogenous Leukemia- Initiating Cells Require Polycomb Group Protein EZH2.
Xie H, Peng C, Huang J, Li BE, Kim W, Smith EC, Fujiwara Y, Qi J, Cheloni G, Das PP, Nguyen M, Li S, Bradner JE, Orkin SH. Xie H, et al. Among authors: smith ec. Cancer Discov. 2016 Nov;6(11):1237-1247. doi: 10.1158/2159-8290.CD-15-1439. Epub 2016 Sep 14. Cancer Discov. 2016. PMID: 27630126 Free PMC article.
Cohort Expansion and Genotype-Phenotype Analysis of RAB11A-Associated Neurodevelopmental Disorder.
Borroto MC, Patel H, Srivastava S, Swanson LC, Keren B, Whalen S, Mignot C, Wang X, Chen Q, Rosenfeld JA, McLean S, Littlejohn RO; Undiagnosed Diseases Network; Emrick L, Burrage LC, Attali R, Lesca G, Acquaviva-Bourdain C, Sarret C, Seaver LH, Platzer K, Bartolomaeus T, Wünsch C, Fischer S, Rodriguez Barreto AM, Granadillo JL, Schreiner E, Brunet T, Schatz UA, Thiffault I, Mullegama SV, Michaud JL, Hamdan FF, Rossignol E, Campeau PM. Borroto MC, et al. Pediatr Neurol. 2024 Nov;160:45-53. doi: 10.1016/j.pediatrneurol.2024.07.010. Epub 2024 Jul 20. Pediatr Neurol. 2024. PMID: 39181022 Free article.
Acute Sympathetic Blockade Improves Insulin-Mediated Microvascular Blood Flow in the Forearm of Adult Human Subjects With Obesity.
Smith EC, Patel JN, Wahba A, Cluckey A, Celedonio J, Park J, Hannah L, Lonce S, Shibao CA, Paranjape SY, Diedrich A, McGuinness O, Wasserman DH, Biaggioni I, Gamboa A. Smith EC, et al. J Am Heart Assoc. 2024 Aug 20;13(16):e030775. doi: 10.1161/JAHA.123.030775. Epub 2024 Aug 9. J Am Heart Assoc. 2024. PMID: 39119951 Free article. Clinical Trial.
405 results