Reinhard FB - Search Results

1

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry.

Franken H, Mathieson T, Childs D, Sweetman GM, Werner T, Tögel I, Doce C, Gade S, Bantscheff M, Drewes G, Reinhard FB, Huber W, Savitski MM. Franken H, et al. Among authors: reinhard fb. Nat Protoc. 2015 Oct;10(10):1567-93. doi: 10.1038/nprot.2015.101. Epub 2015 Sep 17. Nat Protoc. 2015. PMID: 26379230

2

Tracking cancer drugs in living cells by thermal profiling of the proteome.

Savitski MM, Reinhard FB, Franken H, Werner T, Savitski MF, Eberhard D, Martinez Molina D, Jafari R, Dovega RB, Klaeger S, Kuster B, Nordlund P, Bantscheff M, Drewes G. Savitski MM, et al. Among authors: reinhard fb. Science. 2014 Oct 3;346(6205):1255784. doi: 10.1126/science.1255784. Epub 2014 Oct 2. Science. 2014. PMID: 25278616

3

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.

Reinhard FB, Eberhard D, Werner T, Franken H, Childs D, Doce C, Savitski MF, Huber W, Bantscheff M, Savitski MM, Drewes G. Reinhard FB, et al. Nat Methods. 2015 Dec;12(12):1129-31. doi: 10.1038/nmeth.3652. Epub 2015 Nov 2. Nat Methods. 2015. PMID: 26524241

4

Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells.

Eberl HC, Werner T, Reinhard FB, Lehmann S, Thomson D, Chen P, Zhang C, Rau C, Muelbaier M, Drewes G, Drewry D, Bantscheff M. Eberl HC, et al. Among authors: reinhard fb. Sci Rep. 2019 Oct 2;9(1):14159. doi: 10.1038/s41598-019-50335-5. Sci Rep. 2019. PMID: 31578349 Free PMC article.

5

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.

Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Müller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. Bergamini G, et al. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957. Nat Chem Biol. 2012. PMID: 22544264

6

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs.

Unger MS, Schumacher L, Enzlein T, Weigt D, Zamek-Gliszczynski MJ, Schwab M, Nies AT, Drewes G, Schulz S, Reinhard FBM, Hopf C. Unger MS, et al. Among authors: reinhard fbm. Anal Chem. 2020 Sep 1;92(17):11851-11859. doi: 10.1021/acs.analchem.0c02186. Epub 2020 Aug 12. Anal Chem. 2020. PMID: 32867487

7

Screening Pools of Compounds against Multiple Endogenously Expressed Targets in a Chemoproteomics Binding Assay.

Salzer E, Nixon E, Drewes G, Reinhard F, Bergamini G, Rau C. Salzer E, et al. J Lab Autom. 2016 Feb;21(1):133-42. doi: 10.1177/2211068215595355. Epub 2015 Jul 13. J Lab Autom. 2016. PMID: 26169024

8

Clinically Relevant OATP2B1 Inhibitors in Marketed Drug Space.

Unger MS, Mudunuru J, Schwab M, Hopf C, Drewes G, Nies AT, Zamek-Gliszczynski MJ, Reinhard FBM. Unger MS, et al. Among authors: reinhard fbm. Mol Pharm. 2020 Feb 3;17(2):488-498. doi: 10.1021/acs.molpharmaceut.9b00897. Epub 2020 Jan 2. Mol Pharm. 2020. PMID: 31834804

9

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target.

Henley ZA, Amour A, Barton N, Bantscheff M, Bergamini G, Bertrand SM, Convery M, Down K, Dümpelfeld B, Edwards CD, Grandi P, Gore PM, Keeling S, Livia S, Mallett D, Maxwell A, Price M, Rau C, Reinhard FBM, Rowedder J, Rowland P, Taylor JA, Thomas DA, Hessel EM, Hamblin JN. Henley ZA, et al. Among authors: reinhard fbm. J Med Chem. 2020 Jan 23;63(2):638-655. doi: 10.1021/acs.jmedchem.9b01585. Epub 2020 Jan 8. J Med Chem. 2020. PMID: 31855425

10

Working with small molecules: preparing and storing stock solutions and determination of kinetic solubility.

Wolf A, Shimamura S, Reinhard FB. Wolf A, et al. Among authors: reinhard fb. Methods Mol Biol. 2012;803:265-71. doi: 10.1007/978-1-61779-364-6_18. Methods Mol Biol. 2012. PMID: 22065231

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

15 results

Search Page

Filters