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(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.
Dzien P, Tee SS, Kettunen MI, Lyons SK, Larkin TJ, Timm KN, Hu DE, Wright A, Rodrigues TB, Serrao EM, Marco-Rius I, Mannion E, D'Santos P, Kennedy BW, Brindle KM. Dzien P, et al. Among authors: serrao em. Magn Reson Med. 2016 Aug;76(2):391-401. doi: 10.1002/mrm.25879. Epub 2015 Sep 21. Magn Reson Med. 2016. PMID: 26388418 Free PMC article.
Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.
Marco-Rius I, Tayler MC, Kettunen MI, Larkin TJ, Timm KN, Serrao EM, Rodrigues TB, Pileio G, Ardenkjaer-Larsen JH, Levitt MH, Brindle KM. Marco-Rius I, et al. Among authors: serrao em. NMR Biomed. 2013 Dec;26(12):1696-704. doi: 10.1002/nbm.3005. Epub 2013 Aug 15. NMR Biomed. 2013. PMID: 23946252 Free PMC article.
Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.
Gallagher FA, Sladen H, Kettunen MI, Serrao EM, Rodrigues TB, Wright A, Gill AB, McGuire S, Booth TC, Boren J, McIntyre A, Miller JL, Lee SH, Honess D, Day SE, Hu DE, Howat WJ, Harris AL, Brindle KM. Gallagher FA, et al. Among authors: serrao em. Cancer Res. 2015 Oct 1;75(19):4109-18. doi: 10.1158/0008-5472.CAN-15-0857. Epub 2015 Aug 6. Cancer Res. 2015. PMID: 26249175 Free PMC article.
28 results