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Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.
Dao T, Pankov D, Scott A, Korontsvit T, Zakhaleva V, Xu Y, Xiang J, Yan S, de Morais Guerreiro MD, Veomett N, Dubrovsky L, Curcio M, Doubrovina E, Ponomarev V, Liu C, O'Reilly RJ, Scheinberg DA. Dao T, et al. Among authors: dubrovsky l. Nat Biotechnol. 2015 Oct;33(10):1079-86. doi: 10.1038/nbt.3349. Epub 2015 Sep 21. Nat Biotechnol. 2015. PMID: 26389576 Free PMC article.
Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein.
Veomett N, Dao T, Liu H, Xiang J, Pankov D, Dubrovsky L, Whitten JA, Park SM, Korontsvit T, Zakhaleva V, Casey E, Curcio M, Kharas MG, O'Reilly RJ, Liu C, Scheinberg DA. Veomett N, et al. Among authors: dubrovsky l. Clin Cancer Res. 2014 Aug 1;20(15):4036-46. doi: 10.1158/1078-0432.CCR-13-2756. Epub 2014 May 21. Clin Cancer Res. 2014. PMID: 24850840 Free PMC article.
T cell receptor mimic antibodies for cancer therapy.
Dubrovsky L, Dao T, Gejman RS, Brea EJ, Chang AY, Oh CY, Casey E, Pankov D, Scheinberg DA. Dubrovsky L, et al. Oncoimmunology. 2015 Jun 1;5(1):e1049803. doi: 10.1080/2162402X.2015.1049803. eCollection 2016. Oncoimmunology. 2015. PMID: 26942058 Free PMC article. Review.
Randomized Phase 3 LEAP-012 Study: Transarterial Chemoembolization With or Without Lenvatinib Plus Pembrolizumab for Intermediate-Stage Hepatocellular Carcinoma Not Amenable to Curative Treatment.
Llovet JM, Vogel A, Madoff DC, Finn RS, Ogasawara S, Ren Z, Mody K, Li JJ, Siegel AB, Dubrovsky L, Kudo M. Llovet JM, et al. Among authors: dubrovsky l. Cardiovasc Intervent Radiol. 2022 Apr;45(4):405-412. doi: 10.1007/s00270-021-03031-9. Epub 2022 Feb 4. Cardiovasc Intervent Radiol. 2022. PMID: 35119481 Free PMC article. Clinical Trial.
61 results