McCubrey JA - Search Results

1

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia.

Iacovelli S, Ricciardi MR, Allegretti M, Mirabilii S, Licchetta R, Bergamo P, Rinaldo C, Zeuner A, Foà R, Milella M, McCubrey JA, Martelli AM, Tafuri A. Iacovelli S, et al. Among authors: mccubrey ja. Oncotarget. 2015 Oct 13;6(31):32089-103. doi: 10.18632/oncotarget.5156. Oncotarget. 2015. PMID: 26392332 Free PMC article.

2

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, Franklin RA, McCubrey JA. Chang F, et al. Among authors: mccubrey ja. Leukemia. 2003 Mar;17(3):590-603. doi: 10.1038/sj.leu.2402824. Leukemia. 2003. PMID: 12646949 Review.

3

Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.

Blalock WL, Navolanic PM, Steelman LS, Shelton JG, Moye PW, Lee JT, Franklin RA, Mirza A, McMahon M, White MK, McCubrey JA. Blalock WL, et al. Among authors: mccubrey ja. Leukemia. 2003 Jun;17(6):1058-67. doi: 10.1038/sj.leu.2402925. Leukemia. 2003. PMID: 12764369

4

Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.

Carter BZ, Milella M, Tsao T, McQueen T, Schober WD, Hu W, Dean NM, Steelman L, McCubrey JA, Andreeff M. Carter BZ, et al. Among authors: mccubrey ja. Leukemia. 2003 Nov;17(11):2081-9. doi: 10.1038/sj.leu.2403113. Leukemia. 2003. PMID: 12970762

5

Targeted therapy of AML new concepts.

Andreeff M, Milella M, Carter BZ, Tabe Y, Ricciardi MR, Sneed T, Ruvolo P, Contractor R, Tsao T, Schober W, Evans R, McQueen T, Zeng Z, Kornblau SM, McCubrey J, Estey E, Mills GB, Reed JC, Konopleva M. Andreeff M, et al. Ann Hematol. 2004;83 Suppl 1:S51-3. doi: 10.1007/s00277-004-0849-8. Ann Hematol. 2004. PMID: 15124670 No abstract available.

6

Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells.

Bertrand FE, Steelman LS, Chappell WH, Abrams SL, Shelton JG, White ER, Ludwig DL, McCubrey JA. Bertrand FE, et al. Among authors: mccubrey ja. Leukemia. 2006 Jul;20(7):1254-60. doi: 10.1038/sj.leu.2404217. Epub 2006 Apr 27. Leukemia. 2006. PMID: 16642049

7

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.

Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M. Konopleva M, et al. Cancer Cell. 2006 Nov;10(5):375-88. doi: 10.1016/j.ccr.2006.10.006. Cancer Cell. 2006. PMID: 17097560 Free article.

8

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F, Lehmann B, Terrian DM, Milella M, Tafuri A, Stivala F, Libra M, Basecke J, Evangelisti C, Martelli AM, Franklin RA. McCubrey JA, et al. Biochim Biophys Acta. 2007 Aug;1773(8):1263-84. doi: 10.1016/j.bbamcr.2006.10.001. Epub 2006 Oct 7. Biochim Biophys Acta. 2007. PMID: 17126425 Free PMC article. Review.

9

Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.

Tazzari PL, Cappellini A, Ricci F, Evangelisti C, Papa V, Grafone T, Martinelli G, Conte R, Cocco L, McCubrey JA, Martelli AM. Tazzari PL, et al. Among authors: mccubrey ja. Leukemia. 2007 Mar;21(3):427-38. doi: 10.1038/sj.leu.2404523. Epub 2007 Jan 11. Leukemia. 2007. PMID: 17215852

10

The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.

Tazzari PL, Tabellini G, Bortul R, Papa V, Evangelisti C, Grafone T, Martinelli G, McCubrey JA, Martelli AM. Tazzari PL, et al. Among authors: mccubrey ja. Leukemia. 2007 May;21(5):886-96. doi: 10.1038/sj.leu.2404643. Epub 2007 Mar 15. Leukemia. 2007. PMID: 17361225

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