Keogh A - Search Results

1

Impact of MET targeting on tumor-associated angiogenesis and growth of MET mutations-driven models of liver cancer.

Piguet AC, Medová M, Keogh A, Glück AA, Aebersold DM, Dufour JF, Zimmer Y. Piguet AC, et al. Among authors: keogh a. Genes Cancer. 2015 Jul;6(7-8):317-327. doi: 10.18632/genesandcancer.74. Genes Cancer. 2015. PMID: 26413215 Free PMC article.

2

The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants.

Medová M, Pochon B, Streit B, Blank-Liss W, Francica P, Stroka D, Keogh A, Aebersold DM, Blaukat A, Bladt F, Zimmer Y. Medová M, et al. Among authors: keogh a. Mol Cancer Ther. 2013 Nov;12(11):2415-24. doi: 10.1158/1535-7163.MCT-13-0151. Epub 2013 Sep 23. Mol Cancer Ther. 2013. PMID: 24061647

3

Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma.

Piguet AC, Semela D, Keogh A, Wilkens L, Stroka D, Stoupis C, St-Pierre MV, Dufour JF. Piguet AC, et al. Among authors: keogh a. J Hepatol. 2008 Jul;49(1):78-87. doi: 10.1016/j.jhep.2008.03.024. Epub 2008 Apr 28. J Hepatol. 2008. PMID: 18486258

4

Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta.

Banz VM, Medová M, Keogh A, Furer C, Zimmer Y, Candinas D, Stroka D. Banz VM, et al. Among authors: keogh a. Biochim Biophys Acta. 2009 Oct;1793(10):1597-603. doi: 10.1016/j.bbamcr.2009.08.002. Epub 2009 Aug 12. Biochim Biophys Acta. 2009. PMID: 19682504 Free article.

5

Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma.

Gavini J, Dommann N, Jakob MO, Keogh A, Bouchez LC, Karkampouna S, Julio MK, Medova M, Zimmer Y, Schläfli AM, Tschan MP, Candinas D, Stroka D, Banz V. Gavini J, et al. Among authors: keogh a. Cell Death Dis. 2019 Oct 3;10(10):749. doi: 10.1038/s41419-019-1989-z. Cell Death Dis. 2019. PMID: 31582741 Free PMC article.

6

Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury.

Melin N, Sánchez-Taltavull D, Fahrner R, Keogh A, Dosch M, Büchi I, Zimmer Y, Medová M, Beldi G, Aebersold DM, Candinas D, Stroka D. Melin N, et al. Among authors: keogh a. Cell Death Dis. 2021 Apr 6;12(4):366. doi: 10.1038/s41419-021-03654-3. Cell Death Dis. 2021. PMID: 33824326 Free PMC article.

7

Activation of non-ischemic, hypoxia-inducible signalling pathways up-regulate cytoprotective genes in the murine liver.

Plock J, Frese S, Keogh A, Bisch-Knaden S, Ayuni E, Corazza N, Weikert C, Jakob S, Erni D, Dufour JF, Brunner T, Candinas D, Stroka D. Plock J, et al. Among authors: keogh a. J Hepatol. 2007 Oct;47(4):538-45. doi: 10.1016/j.jhep.2007.04.016. Epub 2007 Jun 4. J Hepatol. 2007. PMID: 17599631

8

Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo.

Portmann S, Fahrner R, Lechleiter A, Keogh A, Overney S, Laemmle A, Mikami K, Montani M, Tschan MP, Candinas D, Stroka D. Portmann S, et al. Among authors: keogh a. Mol Cancer Ther. 2013 Apr;12(4):499-508. doi: 10.1158/1535-7163.MCT-12-0700. Epub 2013 Jan 21. Mol Cancer Ther. 2013. PMID: 23339189

9

Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid.

Schneider-Jakob S, Corazza N, Badmann A, Sidler D, Stuber-Roos R, Keogh A, Frese S, Tschan M, Brunner T. Schneider-Jakob S, et al. Among authors: keogh a. Cell Death Dis. 2010 Oct 21;1(10):e86. doi: 10.1038/cddis.2010.66. Cell Death Dis. 2010. PMID: 21368859 Free PMC article.

10

Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions.

Laemmle A, Lechleiter A, Roh V, Schwarz C, Portmann S, Furer C, Keogh A, Tschan MP, Candinas D, Vorburger SA, Stroka D. Laemmle A, et al. Among authors: keogh a. PLoS One. 2012;7(3):e33433. doi: 10.1371/journal.pone.0033433. Epub 2012 Mar 30. PLoS One. 2012. PMID: 22479397 Free PMC article.

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