Inghirami G - Search Results

1

Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors.

Voena C, Menotti M, Mastini C, Di Giacomo F, Longo DL, Castella B, Merlo MEB, Ambrogio C, Wang Q, Minero VG, Poggio T, Martinengo C, D'Amico L, Panizza E, Mologni L, Cavallo F, Altruda F, Butaney M, Capelletti M, Inghirami G, Jänne PA, Chiarle R. Voena C, et al. Among authors: inghirami g. Cancer Immunol Res. 2015 Dec;3(12):1333-1343. doi: 10.1158/2326-6066.CIR-15-0089. Epub 2015 Sep 29. Cancer Immunol Res. 2015. PMID: 26419961 Free PMC article.

2

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death.

Zamo A, Chiarle R, Piva R, Howes J, Fan Y, Chilosi M, Levy DE, Inghirami G. Zamo A, et al. Among authors: inghirami g. Oncogene. 2002 Feb 7;21(7):1038-47. doi: 10.1038/sj.onc.1205152. Oncogene. 2002. PMID: 11850821

3

In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation.

Piva R, Liu J, Chiarle R, Podda A, Pagano M, Inghirami G. Piva R, et al. Among authors: inghirami g. Mol Cell Biol. 2002 Dec;22(23):8375-87. doi: 10.1128/MCB.22.23.8375-8387.2002. Mol Cell Biol. 2002. PMID: 12417738 Free PMC article.

4

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

Chiarle R, Gong JZ, Guasparri I, Pesci A, Cai J, Liu J, Simmons WJ, Dhall G, Howes J, Piva R, Inghirami G. Chiarle R, et al. Among authors: inghirami g. Blood. 2003 Mar 1;101(5):1919-27. doi: 10.1182/blood-2002-05-1343. Epub 2002 Nov 7. Blood. 2003. PMID: 12424201 Free article.

5

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target.

Chiarle R, Simmons WJ, Cai H, Dhall G, Zamo A, Raz R, Karras JG, Levy DE, Inghirami G. Chiarle R, et al. Among authors: inghirami g. Nat Med. 2005 Jun;11(6):623-9. doi: 10.1038/nm1249. Epub 2005 May 15. Nat Med. 2005. PMID: 15895073

6

Follicular origin of a subset of CD5+ diffuse large B-cell lymphomas.

Manazza AD, Bonello L, Pagano M, Chiusa L, Novero D, Stacchini A, Martini G, Vitolo U, Tarella C, Inghirami G, Palestro G, Chiarle R. Manazza AD, et al. Among authors: inghirami g. Am J Clin Pathol. 2005 Aug;124(2):182-90. doi: 10.1309/8EX5-B9JF-HPEK-82BU. Am J Clin Pathol. 2005. PMID: 16040287

7

New and old functions of STAT3: a pivotal target for individualized treatment of cancer.

Inghirami G, Chiarle R, Simmons WJ, Piva R, Schlessinger K, Levy DE. Inghirami G, et al. Cell Cycle. 2005 Sep;4(9):1131-3. doi: 10.4161/cc.4.9.1985. Epub 2005 Sep 30. Cell Cycle. 2005. PMID: 16082218 Review.

8

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

Ambrogio C, Voena C, Manazza AD, Piva R, Riera L, Barberis L, Costa C, Tarone G, Defilippi P, Hirsch E, Boeri Erba E, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R. Ambrogio C, et al. Among authors: inghirami g. Blood. 2005 Dec 1;106(12):3907-16. doi: 10.1182/blood-2005-03-1204. Epub 2005 Aug 16. Blood. 2005. PMID: 16105984 Free PMC article.

9

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas.

Piva R, Chiarle R, Manazza AD, Taulli R, Simmons W, Ambrogio C, D'Escamard V, Pellegrino E, Ponzetto C, Palestro G, Inghirami G. Piva R, et al. Among authors: inghirami g. Blood. 2006 Jan 15;107(2):689-97. doi: 10.1182/blood-2005-05-2125. Epub 2005 Sep 27. Blood. 2006. PMID: 16189272 Free PMC article.

10

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.

Piva R, Pellegrino E, Mattioli M, Agnelli L, Lombardi L, Boccalatte F, Costa G, Ruggeri BA, Cheng M, Chiarle R, Palestro G, Neri A, Inghirami G. Piva R, et al. Among authors: inghirami g. J Clin Invest. 2006 Dec;116(12):3171-82. doi: 10.1172/JCI29401. Epub 2006 Nov 16. J Clin Invest. 2006. PMID: 17111047 Free PMC article.

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