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Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial.
Rasmussen TA, Tolstrup M, Brinkmann CR, Olesen R, Erikstrup C, Solomon A, Winckelmann A, Palmer S, Dinarello C, Buzon M, Lichterfeld M, Lewin SR, Østergaard L, Søgaard OS. Rasmussen TA, et al. Among authors: olesen r. Lancet HIV. 2014 Oct;1(1):e13-21. doi: 10.1016/S2352-3018(14)70014-1. Epub 2014 Sep 15. Lancet HIV. 2014. PMID: 26423811
Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system.
Rasmussen TA, Tolstrup M, Møller HJ, Brinkmann CR, Olesen R, Erikstrup C, Laursen AL, Østergaard L, Søgaard OS. Rasmussen TA, et al. Among authors: olesen r. Open Forum Infect Dis. 2015 Mar 30;2(1):ofv037. doi: 10.1093/ofid/ofv037. eCollection 2015 Jan. Open Forum Infect Dis. 2015. PMID: 26034779 Free PMC article.
Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Olesen R, Vigano S, Rasmussen TA, Søgaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Østergaard L, Tolstrup M, Lichterfeld M. Olesen R, et al. J Virol. 2015 Oct;89(20):10176-89. doi: 10.1128/JVI.01484-15. Epub 2015 Jul 29. J Virol. 2015. PMID: 26223643 Free PMC article. Clinical Trial.
The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.
Søgaard OS, Graversen ME, Leth S, Olesen R, Brinkmann CR, Nissen SK, Kjaer AS, Schleimann MH, Denton PW, Hey-Cunningham WJ, Koelsch KK, Pantaleo G, Krogsgaard K, Sommerfelt M, Fromentin R, Chomont N, Rasmussen TA, Østergaard L, Tolstrup M. Søgaard OS, et al. Among authors: olesen r. PLoS Pathog. 2015 Sep 17;11(9):e1005142. doi: 10.1371/journal.ppat.1005142. eCollection 2015 Sep. PLoS Pathog. 2015. PMID: 26379282 Free PMC article. Clinical Trial.
Immune checkpoints and the HIV-1 reservoir: proceed with caution.
Olesen R, Leth S, Nymann R, Østergaard L, Søgaard OS, Denton PW, Tolstrup M. Olesen R, et al. J Virus Erad. 2016 Jul 1;2(3):183-6. doi: 10.1016/S2055-6640(20)30463-5. J Virus Erad. 2016. PMID: 27482460 Free PMC article. No abstract available.
Broad activation of latent HIV-1 in vivo.
Barton K, Hiener B, Winckelmann A, Rasmussen TA, Shao W, Byth K, Lanfear R, Solomon A, McMahon J, Harrington S, Buzon M, Lichterfeld M, Denton PW, Olesen R, Østergaard L, Tolstrup M, Lewin SR, Søgaard OS, Palmer S. Barton K, et al. Among authors: olesen r. Nat Commun. 2016 Sep 8;7:12731. doi: 10.1038/ncomms12731. Nat Commun. 2016. PMID: 27605062 Free PMC article. Clinical Trial.
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