Gu Y - Search Results

1

Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells.

Cao J, Wang Y, Dong R, Lin G, Zhang N, Wang J, Lin N, Gu Y, Ding L, Ying M, He Q, Yang B. Cao J, et al. Among authors: gu y. Cancer Res. 2015 Nov 15;75(22):4839-51. doi: 10.1158/0008-5472.CAN-15-0711. Epub 2015 Sep 30. Cancer Res. 2015. PMID: 26424695

2

Correction: Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells.

Cao J, Wang Y, Dong R, Lin G, Zhang N, Wang J, Lin N, Gu Y, Ding L, Ying M, He Q, Yang B. Cao J, et al. Among authors: gu y. Cancer Res. 2020 Jun 1;80(11):2421. doi: 10.1158/0008-5472.CAN-20-1147. Cancer Res. 2020. PMID: 32487589 No abstract available.

3

The dual PI3K/mTOR inhibitor NVP-BEZ235 prevents epithelial-mesenchymal transition induced by hypoxia and TGF-β1.

Lin G, Gai R, Chen Z, Wang Y, Liao S, Dong R, Zhu H, Gu Y, He Q, Yang B. Lin G, et al. Among authors: gu y. Eur J Pharmacol. 2014 Apr 15;729:45-53. doi: 10.1016/j.ejphar.2014.02.011. Epub 2014 Feb 20. Eur J Pharmacol. 2014. PMID: 24561043

4

The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer.

Zhu H, Hu Y, Zeng C, Chang L, Ge F, Wang W, Yan F, Zhao Q, Cao J, Ying M, Gu Y, Zheng L, He Q, Yang B. Zhu H, et al. Among authors: gu y. Theranostics. 2020 Jan 12;10(5):2188-2200. doi: 10.7150/thno.39151. eCollection 2020. Theranostics. 2020. PMID: 32104503 Free PMC article.

5

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.

Hunter FW, Young RJ, Shalev Z, Vellanki RN, Wang J, Gu Y, Joshi N, Sreebhavan S, Weinreb I, Goldstein DP, Moffat J, Ketela T, Brown KR, Koritzinsky M, Solomon B, Rischin D, Wilson WR, Wouters BG. Hunter FW, et al. Among authors: gu y. Cancer Res. 2015 Oct 1;75(19):4211-23. doi: 10.1158/0008-5472.CAN-15-1107. Epub 2015 Aug 21. Cancer Res. 2015. PMID: 26297733

6

Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104.

Patterson AV, Ferry DM, Edmunds SJ, Gu Y, Singleton RS, Patel K, Pullen SM, Hicks KO, Syddall SP, Atwell GJ, Yang S, Denny WA, Wilson WR. Patterson AV, et al. Among authors: gu y. Clin Cancer Res. 2007 Jul 1;13(13):3922-32. doi: 10.1158/1078-0432.CCR-07-0478. Clin Cancer Res. 2007. PMID: 17606726

7

Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A.

Gu Y, Patterson AV, Atwell GJ, Chernikova SB, Brown JM, Thompson LH, Wilson WR. Gu Y, et al. Mol Cancer Ther. 2009 Jun;8(6):1714-23. doi: 10.1158/1535-7163.MCT-08-1209. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509245

8

Homologous recombination is the principal pathway for the repair of DNA damage induced by tirapazamine in mammalian cells.

Evans JW, Chernikova SB, Kachnic LA, Banath JP, Sordet O, Delahoussaye YM, Treszezamsky A, Chon BH, Feng Z, Gu Y, Wilson WR, Pommier Y, Olive PL, Powell SN, Brown JM. Evans JW, et al. Among authors: gu y. Cancer Res. 2008 Jan 1;68(1):257-65. doi: 10.1158/0008-5472.CAN-06-4497. Cancer Res. 2008. PMID: 18172318

9

Pre-clinical activity of PR-104 as monotherapy and in combination with sorafenib in hepatocellular carcinoma.

Abbattista MR, Jamieson SM, Gu Y, Nickel JE, Pullen SM, Patterson AV, Wilson WR, Guise CP. Abbattista MR, et al. Among authors: gu y. Cancer Biol Ther. 2015;16(4):610-22. doi: 10.1080/15384047.2015.1017171. Epub 2015 Apr 14. Cancer Biol Ther. 2015. PMID: 25869917 Free PMC article.

10

Reductive metabolism of the dinitrobenzamide mustard anticancer prodrug PR-104 in mice.

Gu Y, Guise CP, Patel K, Abbattista MR, Li J, Sun X, Atwell GJ, Boyd M, Patterson AV, Wilson WR. Gu Y, et al. Cancer Chemother Pharmacol. 2011 Mar;67(3):543-55. doi: 10.1007/s00280-010-1354-5. Epub 2010 May 15. Cancer Chemother Pharmacol. 2011. PMID: 20473609

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