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Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma.
Mieczkowski J, Kocyk M, Nauman P, Gabrusiewicz K, Sielska M, Przanowski P, Maleszewska M, Rajan WD, Pszczolkowska D, Tykocki T, Grajkowska W, Kotulska K, Roszkowski M, Kostkiewicz B, Kaminska B. Mieczkowski J, et al. Oncotarget. 2015 Oct 20;6(32):33077-90. doi: 10.18632/oncotarget.5310. Oncotarget. 2015. PMID: 26427514 Free PMC article.
Genome wide nucleosome landscape shapes 3D chromatin organization.
Fouziya S, Krietenstein N, Mir US, Mieczkowski J, Khan MA, Baba A, Dar MA, Altaf M, Wani AH. Fouziya S, et al. Among authors: mieczkowski j. Sci Adv. 2024 Jun 7;10(23):eadn2955. doi: 10.1126/sciadv.adn2955. Epub 2024 Jun 7. Sci Adv. 2024. PMID: 38848364 Free PMC article.
Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications.
Tyburczy ME, Kotulska K, Pokarowski P, Mieczkowski J, Kucharska J, Grajkowska W, Roszkowski M, Jozwiak S, Kaminska B. Tyburczy ME, et al. Among authors: mieczkowski j. Am J Pathol. 2010 Apr;176(4):1878-90. doi: 10.2353/ajpath.2010.090950. Epub 2010 Feb 4. Am J Pathol. 2010. PMID: 20133820 Free PMC article.
Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells.
Swiatek-Machado K, Mieczkowski J, Ellert-Miklaszewska A, Swierk P, Fokt I, Szymanski S, Skora S, Szeja W, Grynkiewicz G, Lesyng B, Priebe W, Kaminska B. Swiatek-Machado K, et al. Among authors: mieczkowski j. Cancer Biol Ther. 2012 Jun;13(8):657-70. doi: 10.4161/cbt.20083. Epub 2012 Jun 1. Cancer Biol Ther. 2012. PMID: 22555804 Free article.
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia.
Przanowski P, Dabrowski M, Ellert-Miklaszewska A, Kloss M, Mieczkowski J, Kaza B, Ronowicz A, Hu F, Piotrowski A, Kettenmann H, Komorowski J, Kaminska B. Przanowski P, et al. Among authors: mieczkowski j. J Mol Med (Berl). 2014 Mar;92(3):239-54. doi: 10.1007/s00109-013-1090-5. Epub 2013 Oct 6. J Mol Med (Berl). 2014. PMID: 24097101 Free PMC article.
Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells.
Kruczyk M, Przanowski P, Dabrowski M, Swiatek-Machado K, Mieczkowski J, Wallerman O, Ronowicz A, Piotrowski A, Wadelius C, Kaminska B, Komorowski J. Kruczyk M, et al. Among authors: mieczkowski j. Biochim Biophys Acta. 2014 Nov;1839(11):1341-50. doi: 10.1016/j.bbagrm.2014.07.010. Epub 2014 Aug 8. Biochim Biophys Acta. 2014. PMID: 25111868
Environmental stimuli shape microglial plasticity in glioma.
Garofalo S, Porzia A, Mainiero F, Di Angelantonio S, Cortese B, Basilico B, Pagani F, Cignitti G, Chece G, Maggio R, Tremblay ME, Savage J, Bisht K, Esposito V, Bernardini G, Seyfried T, Mieczkowski J, Stepniak K, Kaminska B, Santoni A, Limatola C. Garofalo S, et al. Among authors: mieczkowski j. Elife. 2017 Dec 29;6:e33415. doi: 10.7554/eLife.33415. Elife. 2017. PMID: 29286001 Free PMC article.
90 results