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HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide.
Canella A, Cordero Nieves H, Sborov DW, Cascione L, Radomska HS, Smith E, Stiff A, Consiglio J, Caserta E, Rizzotto L, Zanesi N, Stefano V, Kaur B, Mo X, Byrd JC, Efebera YA, Hofmeister CC, Pichiorri F. Canella A, et al. Oncotarget. 2015 Oct 13;6(31):31134-50. doi: 10.18632/oncotarget.5290. Oncotarget. 2015. PMID: 26429859 Free PMC article.
Histone Deacetylase Inhibitors Enhance the Therapeutic Potential of Reovirus in Multiple Myeloma.
Stiff A, Caserta E, Sborov DW, Nuovo GJ, Mo X, Schlotter SY, Canella A, Smith E, Badway J, Old M, Jaime-Ramirez AC, Yan P, Benson DM, Byrd JC, Baiocchi R, Kaur B, Hofmeister CC, Pichiorri F. Stiff A, et al. Among authors: canella a. Mol Cancer Ther. 2016 May;15(5):830-41. doi: 10.1158/1535-7163.MCT-15-0240-T. Epub 2016 Jan 25. Mol Cancer Ther. 2016. PMID: 26809490 Free PMC article.
A phase 1 trial of the HDAC inhibitor AR-42 in patients with multiple myeloma and T- and B-cell lymphomas.
Sborov DW, Canella A, Hade EM, Mo X, Khountham S, Wang J, Ni W, Poi M, Coss C, Liu Z, Phelps MA, Mortazavi A, Andritsos L, Baiocchi RA, Christian BA, Benson DM, Flynn J, Porcu P, Byrd JC, Pichiorri F, Hofmeister CC. Sborov DW, et al. Among authors: canella a. Leuk Lymphoma. 2017 Oct;58(10):2310-2318. doi: 10.1080/10428194.2017.1298751. Epub 2017 Mar 7. Leuk Lymphoma. 2017. PMID: 28270022 Free PMC article. Clinical Trial.
Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers.
Harshman SW, Canella A, Ciarlariello PD, Agarwal K, Branson OE, Rocci A, Cordero H, Phelps MA, Hade EM, Dubovsky JA, Palumbo A, Rosko A, Byrd JC, Hofmeister CC, Benson DM Jr, Paulaitis ME, Freitas MA, Pichiorri F. Harshman SW, et al. Among authors: canella a. J Proteomics. 2016 Mar 16;136:89-98. doi: 10.1016/j.jprot.2015.12.016. Epub 2016 Jan 13. J Proteomics. 2016. PMID: 26775013 Free PMC article. Clinical Trial.
Characterization of multiple myeloma vesicles by label-free relative quantitation.
Harshman SW, Canella A, Ciarlariello PD, Rocci A, Agarwal K, Smith EM, Talabere T, Efebera YA, Hofmeister CC, Benson DM Jr, Paulaitis ME, Freitas MA, Pichiorri F. Harshman SW, et al. Among authors: canella a. Proteomics. 2013 Oct;13(20):3013-29. doi: 10.1002/pmic.201300142. Proteomics. 2013. PMID: 23983189 Free PMC article.
Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas.
Canella A, Welker AM, Yoo JY, Xu J, Abas FS, Kesanakurti D, Nagarajan P, Beattie CE, Sulman EP, Liu J, Gumin J, Lang FF, Gurcan MN, Kaur B, Sampath D, Puduvalli VK. Canella A, et al. Clin Cancer Res. 2017 Oct 15;23(20):6215-6226. doi: 10.1158/1078-0432.CCR-16-3151. Epub 2017 Jul 5. Clin Cancer Res. 2017. PMID: 28679777 Free PMC article.
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency.
Branchini A, Rizzotto L, Mariani G, Napolitano M, Lapecorella M, Giansily-Blaizot M, Mari R, Canella A, Pinotti M, Bernardi F. Branchini A, et al. Among authors: canella a. Haematologica. 2012 May;97(5):705-9. doi: 10.3324/haematol.2011.049403. Epub 2011 Dec 16. Haematologica. 2012. PMID: 22180436 Free PMC article.
Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma.
Youssef Y, Karkhanis V, Chan WK, Jeney F, Canella A, Zhang X, Sloan S, Prouty A, Helmig-Mason J, Tsyba L, Hanel W, Zheng X, Zhang P, Chung JH, Lucas DM, Kauffman Z, Larkin K, Strohecker AM, Ozer HG, Lapalombella R, Zhou H, Xu-Monette ZY, Young KH, Han R, Nurmemmedov E, Nuovo G, Maddocks K, Byrd JC, Baiocchi RA, Alinari L. Youssef Y, et al. Among authors: canella a. Haematologica. 2021 Nov 1;106(11):2927-2939. doi: 10.3324/haematol.2020.268235. Haematologica. 2021. PMID: 33054136 Free PMC article.
Mesenchymal stem cells from patients to assay bone graft substitutes.
Manfrini M, Di Bona C, Canella A, Lucarelli E, Pellati A, D'Agostino A, Barbanti-Bròdano G, Tognon M. Manfrini M, et al. Among authors: canella a. J Cell Physiol. 2013 Jun;228(6):1229-37. doi: 10.1002/jcp.24276. J Cell Physiol. 2013. PMID: 23129455
56 results