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N-octanoyl dopamine treatment exerts renoprotective properties in acute kidney injury but not in renal allograft recipients.
Klotz S, Pallavi P, Tsagogiorgas C, Zimmer F, Zöllner FG, Binzen U, Greffrath W, Treede RD, Walter J, Harmsen MC, Krämer BK, Hafner M, Yard BA, Hoeger S. Klotz S, et al. Among authors: binzen u. Nephrol Dial Transplant. 2016 Apr;31(4):564-73. doi: 10.1093/ndt/gfv363. Epub 2015 Oct 9. Nephrol Dial Transplant. 2016. PMID: 26454224
N-octanoyl-dopamine is an agonist at the capsaicin receptor TRPV1 and mitigates ischemia-induced [corrected] acute kidney injury in rat.
Tsagogiorgas C, Wedel J, Hottenrott M, Schneider MO, Binzen U, Greffrath W, Treede RD, Theisinger B, Theisinger S, Waldherr R, Krämer BK, Thiel M, Schnuelle P, Yard BA, Hoeger S. Tsagogiorgas C, et al. Among authors: binzen u. PLoS One. 2012;7(8):e43525. doi: 10.1371/journal.pone.0043525. Epub 2012 Aug 20. PLoS One. 2012. PMID: 22916273 Free PMC article.
Analyses of Synthetic N-Acyl Dopamine Derivatives Revealing Different Structural Requirements for Their Anti-inflammatory and Transient-Receptor-Potential-Channel-of-the-Vanilloid-Receptor-Subfamily-Subtype-1 (TRPV1)-Activating Properties.
Pallavi P, Pretze M, Caballero J, Li Y, Hofmann BB, Stamellou E, Klotz S, Wängler C, Wängler B, Loesel R, Roth S, Theisinger B, Moerz H, Binzen U, Greffrath W, Treede RD, Harmsen MC, Krämer BK, Hafner M, Yard BA, Kälsch AI. Pallavi P, et al. Among authors: binzen u. J Med Chem. 2018 Apr 12;61(7):3126-3137. doi: 10.1021/acs.jmedchem.8b00156. Epub 2018 Apr 2. J Med Chem. 2018. PMID: 29543451
11 results