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Page 1
Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
Zhang J, Yang Q, Cross JB, Romero JA, Poutsiaka KM, Epie F, Bevan D, Wang B, Zhang Y, Chavan A, Zhang X, Moy T, Daniel A, Nguyen K, Chamberlain B, Carter N, Shotwell J, Silverman J, Metcalf CA 3rd, Ryan D, Lippa B, Dolle RE. Zhang J, et al. Among authors: silverman j. J Med Chem. 2015 Nov 12;58(21):8503-12. doi: 10.1021/acs.jmedchem.5b00961. Epub 2015 Oct 22. J Med Chem. 2015. PMID: 26460684
Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Zhang J, Yang Q, Romero JA, Cross J, Wang B, Poutsiaka KM, Epie F, Bevan D, Wu Y, Moy T, Daniel A, Chamberlain B, Carter N, Shotwell J, Arya A, Kumar V, Silverman J, Nguyen K, Metcalf CA 3rd, Ryan D, Lippa B, Dolle RE. Zhang J, et al. Among authors: silverman j. ACS Med Chem Lett. 2015 Sep 8;6(10):1080-5. doi: 10.1021/acsmedchemlett.5b00266. eCollection 2015 Oct 8. ACS Med Chem Lett. 2015. PMID: 26487916 Free PMC article.
Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.
Cross JB, Zhang J, Yang Q, Mesleh MF, Romero JA, Wang B, Bevan D, Poutsiaka KM, Epie F, Moy T, Daniel A, Shotwell J, Chamberlain B, Carter N, Andersen O, Barker J, Ryan MD, Metcalf CA 3rd, Silverman J, Nguyen K, Lippa B, Dolle RE. Cross JB, et al. Among authors: silverman j. ACS Med Chem Lett. 2016 Feb 16;7(4):374-8. doi: 10.1021/acsmedchemlett.5b00368. eCollection 2016 Apr 14. ACS Med Chem Lett. 2016. PMID: 27096044 Free PMC article.
Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin.
Hill J, Siedlecki J, Parr I, Morytko M, Yu X, Zhang Y, Silverman J, Controneo N, Laganas V, Li T, Lai JJ, Keith D, Shimer G, Finn J. Hill J, et al. Among authors: silverman j. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4187-91. doi: 10.1016/j.bmcl.2003.07.019. Bioorg Med Chem Lett. 2003. PMID: 14622998
Structure-Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea.
Yin N, Li J, He Y, Herradura P, Pearson A, Mesleh MF, Mascio CT, Howland K, Steenbergen J, Thorne GM, Citron D, Van Praagh AD, Mortin LI, Keith D, Silverman J, Metcalf C. Yin N, et al. Among authors: silverman j. J Med Chem. 2015 Jun 25;58(12):5137-42. doi: 10.1021/acs.jmedchem.5b00366. Epub 2015 Jun 3. J Med Chem. 2015. PMID: 25993059
Array synthesis of novel lipodepsipeptide.
Siedlecki J, Hill J, Parr I, Yu X, Morytko M, Zhang Y, Silverman J, Controneo N, Laganas V, Li T, Li J, Keith D, Shimer G, Finn J. Siedlecki J, et al. Among authors: silverman j. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4245-9. doi: 10.1016/j.bmcl.2003.07.025. Bioorg Med Chem Lett. 2003. PMID: 14623010
Genetic basis for daptomycin resistance in enterococci.
Palmer KL, Daniel A, Hardy C, Silverman J, Gilmore MS. Palmer KL, et al. Among authors: silverman j. Antimicrob Agents Chemother. 2011 Jul;55(7):3345-56. doi: 10.1128/AAC.00207-11. Epub 2011 Apr 18. Antimicrob Agents Chemother. 2011. PMID: 21502617 Free PMC article.
2,030 results