Alexandre EC - Search Results

1

Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β3 -adrenoceptor activation and α1 -adrenoceptor blockade.

Alexandre EC, Kiguti LR, Calmasini FB, Silva FH, da Silva KP, Ferreira R, Ribeiro CA, Mónica FZ, Pupo AS, Antunes E. Alexandre EC, et al. Br J Pharmacol. 2016 Feb;173(3):415-28. doi: 10.1111/bph.13367. Epub 2016 Jan 15. Br J Pharmacol. 2016. PMID: 26493129 Free PMC article.

2

Inhibition of Multidrug Resistance Proteins by MK 571 Enhances Bladder, Prostate, and Urethra Relaxation through cAMP or cGMP Accumulation.

Bertollotto GM, de Oliveira MG, Alexandre EC, Calmasini FB, Passos GR, Antunes E, Mónica FZ. Bertollotto GM, et al. Among authors: alexandre ec. J Pharmacol Exp Ther. 2018 Oct;367(1):138-146. doi: 10.1124/jpet.118.250076. Epub 2018 Aug 14. J Pharmacol Exp Ther. 2018. PMID: 30108158

3

The beta-3 adrenoceptor agonist, mirabegron relaxes isolated prostate from human and rabbit: new therapeutic indication?

Calmasini FB, Candido TZ, Alexandre EC, D'Ancona CA, Silva D, de Oliveira MA, De Nucci G, Antunes E, Mónica FZ. Calmasini FB, et al. Among authors: alexandre ec. Prostate. 2015 Mar 1;75(4):440-7. doi: 10.1002/pros.22930. Epub 2014 Nov 21. Prostate. 2015. PMID: 25417911

4

Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice.

Calmasini FB, de Oliveira MG, Alexandre EC, da Silva FH, da Silva CPV, Candido TZ, Antunes E, Mónica FZ. Calmasini FB, et al. Among authors: alexandre ec. Neurourol Urodyn. 2017 Aug;36(6):1511-1518. doi: 10.1002/nau.23171. Epub 2016 Oct 29. Neurourol Urodyn. 2017. PMID: 27794199

5

How important is the α₁-adrenoceptor in primate and rodent proximal urethra? Sex differences in the contribution of α₁-adrenoceptor to urethral contractility.

Alexandre EC, de Oliveira MG, Campos R, Kiguti LR, Calmasini FB, Silva FH, Grant AD, Yoshimura N, Antunes E. Alexandre EC, et al. Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F1026-F1034. doi: 10.1152/ajprenal.00013.2017. Epub 2017 Mar 15. Am J Physiol Renal Physiol. 2017. PMID: 28298357 Free article.

6

Influence of the periprostatic adipose tissue in obesity-associated mouse urethral dysfunction and oxidative stress: Effect of resveratrol treatment.

Alexandre EC, Calmasini FB, Sponton ACDS, de Oliveira MG, André DM, Silva FH, Delbin MA, Mónica FZ, Antunes E. Alexandre EC, et al. Eur J Pharmacol. 2018 Oct 5;836:25-33. doi: 10.1016/j.ejphar.2018.08.010. Epub 2018 Aug 11. Eur J Pharmacol. 2018. PMID: 30102890

7

Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency.

Calmasini FB, Leiria LO, Alves Junior MJ, Báu FR, Alexandre EC, Silva FH, Mónica FZ, Antunes E. Calmasini FB, et al. Among authors: alexandre ec. Eur J Pharmacol. 2015 Jul 5;758:24-30. doi: 10.1016/j.ejphar.2015.03.057. Epub 2015 Mar 30. Eur J Pharmacol. 2015. PMID: 25835610 Free article.

8

Autonomic dysregulation at multiple sites is implicated in age-associated underactive bladder in female mice.

de Oliveira MG, Alexandre EC, Bonilla-Becerra SM, Bertollotto GM, Justo AFO, Mónica FZ, Antunes E. de Oliveira MG, et al. Among authors: alexandre ec. Neurourol Urodyn. 2019 Jun;38(5):1212-1221. doi: 10.1002/nau.23990. Epub 2019 Apr 1. Neurourol Urodyn. 2019. PMID: 30932250

9

The effects of mirabegron on obesity-induced inflammation and insulin resistance are associated with brown adipose tissue activation but not beiging in the subcutaneous white adipose tissue.

Peres Valgas da Silva C, Calmasini F, Alexandre EC, Raposo HF, Delbin MA, Monica FZ, Zanesco A. Peres Valgas da Silva C, et al. Among authors: alexandre ec. Clin Exp Pharmacol Physiol. 2021 Nov;48(11):1477-1487. doi: 10.1111/1440-1681.13566. Epub 2021 Aug 15. Clin Exp Pharmacol Physiol. 2021. PMID: 34343353

10

Soluble guanylyl cyclase (sGC) degradation and impairment of nitric oxide-mediated responses in urethra from obese mice: reversal by the sGC activator BAY 60-2770.

Alexandre EC, Leiria LO, Silva FH, Mendes-Silvério CB, Calmasini FB, Davel AP, Mónica FZ, De Nucci G, Antunes E. Alexandre EC, et al. J Pharmacol Exp Ther. 2014 Apr;349(1):2-9. doi: 10.1124/jpet.113.211029. Epub 2014 Jan 13. J Pharmacol Exp Ther. 2014. PMID: 24421320

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