Klein T - Search Results

1

Combination of Telmisartan and Linagliptin Preserves Pancreatic Islet Cell Function and Morphology in db/db Mice.

Zhao S, Chan LK, Chen L, Cheng TW, Klein T, Leung PS. Zhao S, et al. Among authors: klein t. Pancreas. 2016 Apr;45(4):584-92. doi: 10.1097/MPA.0000000000000505. Pancreas. 2016. PMID: 26495783

2

Effects of combining linagliptin treatment with BI-38335, a novel SGLT2 inhibitor, on pancreatic islet function and inflammation in db/db mice.

Chen L, Klein T, Leung PS. Chen L, et al. Among authors: klein t. Curr Mol Med. 2012 Sep;12(8):995-1004. doi: 10.2174/156652412802480970. Curr Mol Med. 2012. PMID: 22804249

3

Linagliptin alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis.

Klein T, Fujii M, Sandel J, Shibazaki Y, Wakamatsu K, Mark M, Yoneyama H. Klein T, et al. Med Mol Morphol. 2014 Sep;47(3):137-49. doi: 10.1007/s00795-013-0053-9. Epub 2013 Sep 19. Med Mol Morphol. 2014. PMID: 24048504

4

Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension.

Chaykovska L, Alter ML, von Websky K, Hohmann M, Tsuprykov O, Reichetzeder C, Kutil B, Kraft R, Klein T, Hocher B. Chaykovska L, et al. Among authors: klein t. J Hypertens. 2013 Nov;31(11):2290-8; discussion 2299. doi: 10.1097/HJH.0b013e3283649b4d. J Hypertens. 2013. PMID: 24077249

5

Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats.

Jones RB, Vickers SP, Cheetham SC, Headland KR, Mark M, Klein T. Jones RB, et al. Among authors: klein t. Eur J Pharmacol. 2014 Apr 15;729:59-66. doi: 10.1016/j.ejphar.2014.02.004. Epub 2014 Feb 14. Eur J Pharmacol. 2014. PMID: 24530555 Free article.

6

Linagliptin enhances neural stem cell proliferation after stroke in type 2 diabetic mice.

Darsalia V, Olverling A, Larsson M, Mansouri S, Nathanson D, Nyström T, Klein T, Sjöholm Å, Patrone C. Darsalia V, et al. Among authors: klein t. Regul Pept. 2014 May;190-191:25-31. doi: 10.1016/j.regpep.2014.05.001. Epub 2014 May 10. Regul Pept. 2014. PMID: 24821550

7

The SGLT2 inhibitor empagliflozin improves insulin sensitivity in db/db mice both as monotherapy and in combination with linagliptin.

Kern M, Klöting N, Mark M, Mayoux E, Klein T, Blüher M. Kern M, et al. Among authors: klein t. Metabolism. 2016 Feb;65(2):114-23. doi: 10.1016/j.metabol.2015.10.010. Epub 2015 Nov 13. Metabolism. 2016. PMID: 26773934

8

The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy.

Tsuprykov O, Ando R, Reichetzeder C, von Websky K, Antonenko V, Sharkovska Y, Chaykovska L, Rahnenführer J, Hasan AA, Tammen H, Alter M, Klein T, Ueda S, Yamagishi SI, Okuda S, Hocher B. Tsuprykov O, et al. Among authors: klein t. Kidney Int. 2016 May;89(5):1049-1061. doi: 10.1016/j.kint.2016.01.016. Epub 2016 Mar 24. Kidney Int. 2016. PMID: 27083282 Free article.

9

Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice.

Manrique C, Habibi J, Aroor AR, Sowers JR, Jia G, Hayden MR, Garro M, Martinez-Lemus LA, Ramirez-Perez FI, Klein T, Meininger GA, DeMarco VG. Manrique C, et al. Among authors: klein t. Cardiovasc Diabetol. 2016 Jul 8;15:94. doi: 10.1186/s12933-016-0414-5. Cardiovasc Diabetol. 2016. PMID: 27391040 Free PMC article.

10

Vascular effects of linagliptin in non-obese diabetic mice are glucose-independent and involve positive modulation of the endothelial nitric oxide synthase (eNOS)/caveolin-1 (CAV-1) pathway.

Vellecco V, Mitidieri E, Gargiulo A, Brancaleone V, Matassa D, Klein T, Esposito F, Cirino G, Bucci M. Vellecco V, et al. Among authors: klein t. Diabetes Obes Metab. 2016 Dec;18(12):1236-1243. doi: 10.1111/dom.12750. Epub 2016 Aug 30. Diabetes Obes Metab. 2016. PMID: 27460695

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