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Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation.
Pfister SX, Markkanen E, Jiang Y, Sarkar S, Woodcock M, Orlando G, Mavrommati I, Pai CC, Zalmas LP, Drobnitzky N, Dianov GL, Verrill C, Macaulay VM, Ying S, La Thangue NB, D'Angiolella V, Ryan AJ, Humphrey TC. Pfister SX, et al. Cancer Cell. 2015 Nov 9;28(5):557-568. doi: 10.1016/j.ccell.2015.09.015. Cancer Cell. 2015. PMID: 26602815 Free PMC article.
An essential role for dNTP homeostasis following CDK-induced replication stress.
Pai CC, Hsu KF, Durley SC, Keszthelyi A, Kearsey SE, Rallis C, Folkes LK, Deegan R, Wilkins SE, Pfister SX, De León N, Schofield CJ, Bähler J, Carr AM, Humphrey TC. Pai CC, et al. Among authors: pfister sx. J Cell Sci. 2019 Mar 25;132(6):jcs226969. doi: 10.1242/jcs.226969. J Cell Sci. 2019. PMID: 30674555 Free PMC article.
SET-ting the stage for DNA repair.
Jha DK, Pfister SX, Humphrey TC, Strahl BD. Jha DK, et al. Among authors: pfister sx. Nat Struct Mol Biol. 2014 Aug;21(8):655-7. doi: 10.1038/nsmb.2866. Nat Struct Mol Biol. 2014. PMID: 25093525 No abstract available.
Keys to the kingdom.
Wong SC, Sasportas LS, Richardson K, Gordon BR, Jayatunga MK, Shalizi A, Pfister SX, Stanzl EG, Chui C, Mathur M, Thomsen SK, Shetty C, Pliuskys L, Mehra A, Bahar H, Godec J, Jong S, Perez DA. Wong SC, et al. Among authors: pfister sx. Nat Biotechnol. 2015 Mar;33(3):232-6. doi: 10.1038/nbt.3159. Epub 2015 Feb 26. Nat Biotechnol. 2015. PMID: 25748908 No abstract available.
Combinatorial immunotherapy induces tumor-infiltrating CD8+ T cells with distinct functional, migratory, and stem-like properties.
Van Braeckel-Budimir N, Dolina JS, Wei J, Wang X, Chen SH, Santiago P, Tu G, Micci L, Al-Khami AA, Pfister S, Ram S, Sundar P, Thomas G, Long H, Yang W, Potluri S, Salek-Ardakani S. Van Braeckel-Budimir N, et al. J Immunother Cancer. 2021 Dec;9(12):e003614. doi: 10.1136/jitc-2021-003614. J Immunother Cancer. 2021. PMID: 34903555 Free PMC article.
13 results