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IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
Su EW, Moore CJ, Suriano S, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Andrijauskaite K, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li Z, Cole DJ, Rubinstein MP. Su EW, et al. Among authors: doedens al. Sci Transl Med. 2015 Oct 28;7(311):311ra170. doi: 10.1126/scitranslmed.aac8155. Sci Transl Med. 2015. PMID: 26511507 Free PMC article.
Differentiation of CD8 memory T cells depends on Foxo1.
Hess Michelini R, Doedens AL, Goldrath AW, Hedrick SM. Hess Michelini R, et al. Among authors: doedens al. J Exp Med. 2013 Jun 3;210(6):1189-200. doi: 10.1084/jem.20130392. Epub 2013 May 27. J Exp Med. 2013. PMID: 23712431 Free PMC article.
FOXO transcription factors throughout T cell biology.
Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. Hedrick SM, et al. Among authors: doedens al. Nat Rev Immunol. 2012 Sep;12(9):649-61. doi: 10.1038/nri3278. Nat Rev Immunol. 2012. PMID: 22918467 Free PMC article. Review.
S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.
Tyrakis PA, Palazon A, Macias D, Lee KL, Phan AT, Veliça P, You J, Chia GS, Sim J, Doedens A, Abelanet A, Evans CE, Griffiths JR, Poellinger L, Goldrath AW, Johnson RS. Tyrakis PA, et al. Nature. 2016 Dec 8;540(7632):236-241. doi: 10.1038/nature20165. Epub 2016 Oct 26. Nature. 2016. PMID: 27798602 Free PMC article.
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