Renn C - Search Results

1

Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling.

Phoa AF, Browne S, Gurgis FM, Åkerfeldt MC, Döbber A, Renn C, Peifer C, Stringer BW, Day BW, Wong C, Chircop M, Johns TG, Kassiou M, Munoz L. Phoa AF, et al. Among authors: renn c. Biochem Pharmacol. 2015 Dec 15;98(4):587-601. doi: 10.1016/j.bcp.2015.10.014. Epub 2015 Oct 28. Biochem Pharmacol. 2015. PMID: 26519552

2

Design, Synthesis, and Characterization of a Photoactivatable Caged Prodrug of Imatinib.

Zindler M, Pinchuk B, Renn C, Horbert R, Döbber A, Peifer C. Zindler M, et al. Among authors: renn c. ChemMedChem. 2015 Aug;10(8):1335-8. doi: 10.1002/cmdc.201500163. Epub 2015 Jun 15. ChemMedChem. 2015. PMID: 26076342

3

From Type I to Type II: Design, Synthesis, and Characterization of Potent Pyrazin-2-ones as DFG-Out Inhibitors of PDGFRβ.

Bethke E, Pinchuk B, Renn C, Witt L, Schlosser J, Peifer C. Bethke E, et al. Among authors: renn c. ChemMedChem. 2016 Dec 16;11(24):2664-2674. doi: 10.1002/cmdc.201600494. Epub 2016 Nov 25. ChemMedChem. 2016. PMID: 27885822

4

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.

Lopez V, Schäkel L, Schuh HJM, Schmidt MS, Mirza S, Renn C, Pelletier J, Lee SY, Sévigny J, Alban S, Bendas G, Müller CE. Lopez V, et al. Among authors: renn c. Mar Drugs. 2021 Jan 22;19(2):51. doi: 10.3390/md19020051. Mar Drugs. 2021. PMID: 33499103 Free PMC article.

5

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Nassir M, Arad U, Lee SY, Journo S, Mirza S, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Nassir M, et al. Among authors: renn c. Purinergic Signal. 2019 Jun;15(2):247-263. doi: 10.1007/s11302-019-09649-2. Epub 2019 Apr 25. Purinergic Signal. 2019. PMID: 31025169 Free PMC article.

6

Adenine-(methoxy)-ethoxy-P_α,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Nassir M, Mirza S, Arad U, Lee S, Rafehi M, Yaw Attah I, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Nassir M, et al. Among authors: renn c. Org Biomol Chem. 2019 Nov 27;17(46):9913-9923. doi: 10.1039/c9ob02199j. Org Biomol Chem. 2019. PMID: 31720670

7

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

Bhattarai S, Pippel J, Scaletti E, Idris R, Freundlieb M, Rolshoven G, Renn C, Lee SY, Abdelrahman A, Zimmermann H, El-Tayeb A, Müller CE, Sträter N. Bhattarai S, et al. Among authors: renn c. J Med Chem. 2020 Mar 26;63(6):2941-2957. doi: 10.1021/acs.jmedchem.9b01611. Epub 2020 Feb 28. J Med Chem. 2020. PMID: 32045236

8

Fluorescent Probes for Ecto-5'-nucleotidase (CD73).

Schmies CC, Rolshoven G, Idris RM, Losenkova K, Renn C, Schäkel L, Al-Hroub H, Wang Y, Garofano F, Schmidt-Wolf IGH, Zimmermann H, Yegutkin GG, Müller CE. Schmies CC, et al. Among authors: renn c. ACS Med Chem Lett. 2020 Sep 3;11(11):2253-2260. doi: 10.1021/acsmedchemlett.0c00391. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214837 Free PMC article.

9

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

Junker A, Renn C, Dobelmann C, Namasivayam V, Jain S, Losenkova K, Irjala H, Duca S, Balasubramanian R, Chakraborty S, Börgel F, Zimmermann H, Yegutkin GG, Müller CE, Jacobson KA. Junker A, et al. Among authors: renn c. J Med Chem. 2019 Apr 11;62(7):3677-3695. doi: 10.1021/acs.jmedchem.9b00164. Epub 2019 Mar 21. J Med Chem. 2019. PMID: 30895781 Free PMC article.

10

Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity.

Gammelgaard OL, Terp MG, Renn C, Labrijn AF, Hamaker O, Nielsen AY, Vever H, Hansen SW, Gjerstorff MF, Müller CE, Parren PW, Ditzel HJ. Gammelgaard OL, et al. Among authors: renn c. J Immunother Cancer. 2022 Sep;10(9):e004554. doi: 10.1136/jitc-2022-004554. J Immunother Cancer. 2022. PMID: 36096528 Free PMC article.

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