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Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.
Singh V, Chassaing B, Zhang L, San Yeoh B, Xiao X, Kumar M, Baker MT, Cai J, Walker R, Borkowski K, Harvatine KJ, Singh N, Shearer GC, Ntambi JM, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M. Singh V, et al. Among authors: singh n. Cell Metab. 2015 Dec 1;22(6):983-96. doi: 10.1016/j.cmet.2015.09.028. Epub 2015 Oct 29. Cell Metab. 2015. PMID: 26525535 Free PMC article.
An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis.
Sivaprakasam S, Gurav A, Paschall AV, Coe GL, Chaudhary K, Cai Y, Kolhe R, Martin P, Browning D, Huang L, Shi H, Sifuentes H, Vijay-Kumar M, Thompson SA, Munn DH, Mellor A, McGaha TL, Shiao P, Cutler CW, Liu K, Ganapathy V, Li H, Singh N. Sivaprakasam S, et al. Among authors: singh n. Oncogenesis. 2016 Jun 27;5(6):e238. doi: 10.1038/oncsis.2016.38. Oncogenesis. 2016. PMID: 27348268 Free PMC article.
Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.
Jadeja RN, Jones MA, Fromal O, Powell FL, Khurana S, Singh N, Martin PM. Jadeja RN, et al. Among authors: singh n. Aging (Albany NY). 2019 Jan 18;11(2):386-400. doi: 10.18632/aging.101743. Aging (Albany NY). 2019. PMID: 30659164 Free PMC article.
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.
Zimmerman MA, Singh N, Martin PM, Thangaraju M, Ganapathy V, Waller JL, Shi H, Robertson KD, Munn DH, Liu K. Zimmerman MA, et al. Among authors: singh n. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1405-15. doi: 10.1152/ajpgi.00543.2011. Epub 2012 Apr 19. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22517765 Free PMC article.
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