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Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.
Baghdasaryan A, Fuchs CD, Österreicher CH, Lemberger UJ, Halilbasic E, Påhlman I, Graffner H, Krones E, Fickert P, Wahlström A, Ståhlman M, Paumgartner G, Marschall HU, Trauner M. Baghdasaryan A, et al. Among authors: stahlman m. J Hepatol. 2016 Mar;64(3):674-81. doi: 10.1016/j.jhep.2015.10.024. Epub 2015 Oct 31. J Hepatol. 2016. PMID: 26529078 Free article.
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
Krones E, Eller K, Pollheimer MJ, Racedo S, Kirsch AH, Frauscher B, Wahlström A, Ståhlman M, Trauner M, Grahammer F, Huber TB, Wagner K, Rosenkranz AR, Marschall HU, Fickert P. Krones E, et al. Among authors: stahlman m. J Hepatol. 2017 Jul;67(1):110-119. doi: 10.1016/j.jhep.2017.02.019. Epub 2017 Feb 27. J Hepatol. 2017. PMID: 28242240
Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile acids.
Fuchs CD, Paumgartner G, Mlitz V, Kunczer V, Halilbasic E, Leditznig N, Wahlström A, Ståhlman M, Thüringer A, Kashofer K, Stojakovic T, Marschall HU, Trauner M. Fuchs CD, et al. Among authors: stahlman m. Gut. 2018 Sep;67(9):1683-1691. doi: 10.1136/gutjnl-2017-314553. Epub 2018 Apr 10. Gut. 2018. PMID: 29636383 Free PMC article.
Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
Al-Dury S, Wahlström A, Panzitt K, Thorell A, Ståhlman M, Trauner M, Fickert P, Bäckhed F, Fändriks L, Wagner M, Marschall HU. Al-Dury S, et al. Among authors: stahlman m. J Hepatol. 2019 Nov;71(5):986-991. doi: 10.1016/j.jhep.2019.06.011. Epub 2019 Jun 27. J Hepatol. 2019. PMID: 31254596 Clinical Trial.
Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis via immunomodulatory effects.
Fuchs CD, Dixon ED, Hendrikx T, Mlitz V, Wahlström A, Ståhlman M, Scharnagl H, Stojakovic T, Binder CJ, Marschall HU, Trauner M. Fuchs CD, et al. Among authors: stahlman m. Hepatol Commun. 2022 Sep;6(9):2368-2378. doi: 10.1002/hep4.1998. Epub 2022 Jun 12. Hepatol Commun. 2022. PMID: 35691019 Free PMC article.
Cyp3a11 is not essential for the formation of murine bile acids.
Wahlström A, Al-Dury S, Ståhlman M, Bäckhed F, Marschall HU. Wahlström A, et al. Among authors: stahlman m. Biochem Biophys Rep. 2017 Mar 8;10:70-75. doi: 10.1016/j.bbrep.2017.02.011. eCollection 2017 Jul. Biochem Biophys Rep. 2017. PMID: 28955737 Free PMC article.
286 results