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Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position.
Bioorg Med Chem Lett. 2015 Dec 15;25(24):5748-51. doi: 10.1016/j.bmcl.2015.10.076. Epub 2015 Oct 31.
Bioorg Med Chem Lett. 2015.
PMID: 26531150
Synthesis, GluN2B affinity and selectivity of benzo[7]annulen-7-amines.
Gawaskar S, Schepmann D, Bonifazi A, Wünsch B.
Gawaskar S, et al.
Bioorg Med Chem. 2014 Dec 1;22(23):6638-6646. doi: 10.1016/j.bmc.2014.10.004. Epub 2014 Oct 12.
Bioorg Med Chem. 2014.
PMID: 25458498
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Design, Synthesis, Pharmacological Evaluation and Docking Studies of GluN2B-Selective NMDA Receptor Antagonists with a Benzo[7]annulen-7-amine Scaffold.
Gawaskar S, Temme L, Schreiber JA, Schepmann D, Bonifazi A, Robaa D, Sippl W, Strutz-Seebohm N, Seebohm G, Wünsch B.
Gawaskar S, et al.
ChemMedChem. 2017 Aug 8;12(15):1212-1222. doi: 10.1002/cmdc.201700311. Epub 2017 Jul 27.
ChemMedChem. 2017.
PMID: 28749574
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Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds.
Temme L, Bechthold E, Schreiber JA, Gawaskar S, Schepmann D, Robaa D, Sippl W, Seebohm G, Wünsch B.
Temme L, et al. Among authors: gawaskar s.
Eur J Med Chem. 2020 Mar 15;190:112138. doi: 10.1016/j.ejmech.2020.112138. Epub 2020 Feb 10.
Eur J Med Chem. 2020.
PMID: 32070917
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