Hansen AH - Search Results

1

A Markov chain model for N-linked protein glycosylation--towards a low-parameter tool for model-driven glycoengineering.

Spahn PN, Hansen AH, Hansen HG, Arnsdorf J, Kildegaard HF, Lewis NE. Spahn PN, et al. Among authors: hansen hg, hansen ah. Metab Eng. 2016 Jan;33:52-66. doi: 10.1016/j.ymben.2015.10.007. Epub 2015 Oct 29. Metab Eng. 2016. PMID: 26537759 Free PMC article.

2

One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment.

Grav LM, Lee JS, Gerling S, Kallehauge TB, Hansen AH, Kol S, Lee GM, Pedersen LE, Kildegaard HF. Grav LM, et al. Among authors: hansen ah. Biotechnol J. 2015 Sep;10(9):1446-56. doi: 10.1002/biot.201500027. Epub 2015 Apr 30. Biotechnol J. 2015. PMID: 25864574

3

Predictive glycoengineering of biosimilars using a Markov chain glycosylation model.

Spahn PN, Hansen AH, Kol S, Voldborg BG, Lewis NE. Spahn PN, et al. Among authors: hansen ah. Biotechnol J. 2017 Feb;12(2):10.1002/biot.201600489. doi: 10.1002/biot.201600489. Epub 2016 Dec 28. Biotechnol J. 2017. PMID: 27860290 Free PMC article.

4

Baicalein Reduces Oxidative Stress in CHO Cell Cultures and Improves Recombinant Antibody Productivity.

Ha TK, Hansen AH, Kol S, Kildegaard HF, Lee GM. Ha TK, et al. Among authors: hansen ah. Biotechnol J. 2018 Mar;13(3):e1700425. doi: 10.1002/biot.201700425. Epub 2017 Nov 15. Biotechnol J. 2018. PMID: 29125225

5

CRISPR/Cas9-Multiplexed Editing of Chinese Hamster Ovary B4Gal-T1, 2, 3, and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins.

Amann T, Hansen AH, Kol S, Lee GM, Andersen MR, Kildegaard HF. Amann T, et al. Among authors: hansen ah. Biotechnol J. 2018 Oct;13(10):e1800111. doi: 10.1002/biot.201800111. Epub 2018 Jul 2. Biotechnol J. 2018. PMID: 29862652

6

Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles.

Amann T, Hansen AH, Kol S, Hansen HG, Arnsdorf J, Nallapareddy S, Voldborg B, Lee GM, Andersen MR, Kildegaard HF. Amann T, et al. Among authors: hansen hg, hansen ah. Metab Eng. 2019 Mar;52:143-152. doi: 10.1016/j.ymben.2018.11.014. Epub 2018 Dec 1. Metab Eng. 2019. PMID: 30513349

7

BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture.

Ha TK, Hansen AH, Kildegaard HF, Lee GM. Ha TK, et al. Among authors: hansen ah. Biotechnol J. 2019 Oct;14(10):e1900130. doi: 10.1002/biot.201900130. Epub 2019 Jul 5. Biotechnol J. 2019. PMID: 31161665

8

Awakening dormant glycosyltransferases in CHO cells with CRISPRa.

Karottki KJC, Hefzi H, Xiong K, Shamie I, Hansen AH, Li S, Pedersen LE, Li S, Lee JS, Lee GM, Kildegaard HF, Lewis NE. Karottki KJC, et al. Among authors: hansen ah. Biotechnol Bioeng. 2020 Feb;117(2):593-598. doi: 10.1002/bit.27199. Epub 2019 Nov 12. Biotechnol Bioeng. 2020. PMID: 31631317 Free PMC article.

9

Knockout of sialidase and pro-apoptotic genes in Chinese hamster ovary cells enables the production of recombinant human erythropoietin in fed-batch cultures.

Ha TK, Hansen AH, Kildegaard HF, Lee GM. Ha TK, et al. Among authors: hansen ah. Metab Eng. 2020 Jan;57:182-192. doi: 10.1016/j.ymben.2019.11.008. Epub 2019 Nov 27. Metab Eng. 2020. PMID: 31785386

10

A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering.

Liang C, Chiang AWT, Hansen AH, Arnsdorf J, Schoffelen S, Sorrentino JT, Kellman BP, Bao B, Voldborg BG, Lewis NE. Liang C, et al. Among authors: hansen ah. Curr Res Biotechnol. 2020 Nov;2:22-36. doi: 10.1016/j.crbiot.2020.01.001. Epub 2020 Jan 23. Curr Res Biotechnol. 2020. PMID: 32285041 Free PMC article.

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