Verdile G - Search Results

1

Validation and Characterization of a Novel Peptide That Binds Monomeric and Aggregated β-Amyloid and Inhibits the Formation of Neurotoxic Oligomers.

Barr RK, Verdile G, Wijaya LK, Morici M, Taddei K, Gupta VB, Pedrini S, Jin L, Nicolazzo JA, Knock E, Fraser PE, Martins RN. Barr RK, et al. Among authors: verdile g. J Biol Chem. 2016 Jan 8;291(2):547-59. doi: 10.1074/jbc.M115.679993. Epub 2015 Nov 4. J Biol Chem. 2016. PMID: 26538562 Free PMC article.

We have previously reported that a novel 15-amino acid peptide (15-mer), isolated via phage display screening, targeted Abeta and attenuated its neurotoxicity (Taddei, K., Laws, S. M., Verdile, G., Munns, S., D'Costa, K., Harvey, A. R., Martins, I. J., Hill, F., Lev …

We have previously reported that a novel 15-amino acid peptide (15-mer), isolated via phage display screening, targeted Abeta and attenuated …

2

Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.

Verdile G, Martins RN, Duthie M, Holmes E, St George-Hyslop PH, Fraser PE. Verdile G, et al. J Biol Chem. 2000 Jul 7;275(27):20794-8. doi: 10.1074/jbc.C000208200. J Biol Chem. 2000. PMID: 10801777 Free article.

3

Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.

Miklossy J, Taddei K, Suva D, Verdile G, Fonte J, Fisher C, Gnjec A, Ghika J, Suard F, Mehta PD, McLean CA, Masters CL, Brooks WS, Martins RN. Miklossy J, et al. Among authors: verdile g. Neurobiol Aging. 2003 Sep;24(5):655-62. doi: 10.1016/s0197-4580(02)00192-6. Neurobiol Aging. 2003. PMID: 12885573

4

Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression.

Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Liu T, et al. Among authors: verdile g. J Neurochem. 2004 Feb;88(3):554-63. doi: 10.1046/j.1471-4159.2003.02196.x. J Neurochem. 2004. PMID: 14720205 Free article.

5

Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.

Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Bowen RL, et al. Among authors: verdile g. J Biol Chem. 2004 May 7;279(19):20539-45. doi: 10.1074/jbc.M311993200. Epub 2004 Feb 9. J Biol Chem. 2004. PMID: 14871891 Free article.

6

Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells.

Verdile G, Groth D, Mathews PM, St George-Hyslop P, Fraser PE, Ramabhadran TV, Kwok JB, Schofield PR, Carter T, Gandy S, Martins RN. Verdile G, et al. Mol Psychiatry. 2004 Jun;9(6):594-602. doi: 10.1038/sj.mp.4001458. Mol Psychiatry. 2004. PMID: 14993906

7

The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught?

Verdile G, Fuller S, Atwood CS, Laws SM, Gandy SE, Martins RN. Verdile G, et al. Pharmacol Res. 2004 Oct;50(4):397-409. doi: 10.1016/j.phrs.2003.12.028. Pharmacol Res. 2004. PMID: 15304237 Review.

8

Protein markers for Alzheimer disease in the frontal cortex and cerebellum.

Verdile G, Gnjec A, Miklossy J, Fonte J, Veurink G, Bates K, Kakulas B, Mehta PD, Milward EA, Tan N, Lareu R, Lim D, Dharmarajan A, Martins RN. Verdile G, et al. Neurology. 2004 Oct 26;63(8):1385-92. doi: 10.1212/01.wnl.0000141848.45315.a6. Neurology. 2004. PMID: 15505153

9

Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells.

Carter TL, Verdile G, Groth D, Bogush A, Thomas S, Shen P, Fraser PE, Mathews P, Nixon RA, Ehrlich ME, Kwok JB, St George-Hyslop P, Schofield P, Li Y, Yang A, Martins RN, Gandy S. Carter TL, et al. Among authors: verdile g. Alzheimer Dis Assoc Disord. 2004 Oct-Dec;18(4):261-3. Alzheimer Dis Assoc Disord. 2004. PMID: 15592142

10

Plasma Abeta42 correlates positively with increased body fat in healthy individuals.

Balakrishnan K, Verdile G, Mehta PD, Beilby J, Nolan D, Galvão DA, Newton R, Gandy SE, Martins RN. Balakrishnan K, et al. Among authors: verdile g. J Alzheimers Dis. 2005 Dec;8(3):269-82. doi: 10.3233/jad-2005-8305. J Alzheimers Dis. 2005. PMID: 16340084

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