Sharpe J - Search Results

1

A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies.

Walter HS, Rule SA, Dyer MJ, Karlin L, Jones C, Cazin B, Quittet P, Shah N, Hutchinson CV, Honda H, Duffy K, Birkett J, Jamieson V, Courtenay-Luck N, Yoshizawa T, Sharpe J, Ohno T, Abe S, Nishimura A, Cartron G, Morschhauser F, Fegan C, Salles G. Walter HS, et al. Among authors: sharpe j. Blood. 2016 Jan 28;127(4):411-9. doi: 10.1182/blood-2015-08-664086. Epub 2015 Nov 5. Blood. 2016. PMID: 26542378 Free PMC article. Clinical Trial.

2

Randomised clinical trial: exploratory phase 2 study of ONO-2952 in diarrhoea-predominant irritable bowel syndrome.

Whitehead WE, Duffy K, Sharpe J, Nabata T, Bruce M. Whitehead WE, et al. Among authors: sharpe j. Aliment Pharmacol Ther. 2017 Jan;45(1):14-26. doi: 10.1111/apt.13839. Epub 2016 Nov 7. Aliment Pharmacol Ther. 2017. PMID: 27910150 Free PMC article. Clinical Trial.

3

First Clinical Experience with ONO-4232: A Randomized, Double-blind, Placebo-controlled Healthy Volunteer Study of a Novel Lusitropic Agent for Acutely Decompensated Heart Failure.

Ward CL, Jamieson V, Nabata T, Sharpe J, Dozono K, Suto F, Hashimoto Y, Gussak I. Ward CL, et al. Among authors: sharpe j. Clin Ther. 2016 May;38(5):1109-21. doi: 10.1016/j.clinthera.2016.02.019. Epub 2016 Mar 19. Clin Ther. 2016. PMID: 27001444 Free article. Clinical Trial.

4

Editorial: ONO-2952 in irritable bowel syndrome with diarrhoea - authors' reply.

Whitehead WE, Duffy K, Sharpe J, Nabata T, Bruce M. Whitehead WE, et al. Among authors: sharpe j. Aliment Pharmacol Ther. 2017 Apr;45(7):1005. doi: 10.1111/apt.13957. Aliment Pharmacol Ther. 2017. PMID: 28256085 No abstract available.

5

Morning vs evening dosing of the cathepsin K inhibitor ONO-5334: effects on bone resorption in postmenopausal women in a randomized, phase 1 trial.

Eastell R, Dijk DJ, Small M, Greenwood A, Sharpe J, Yamada H, Yuba M, Tanimoto M, Deacon S. Eastell R, et al. Among authors: sharpe j. Osteoporos Int. 2016 Jan;27(1):309-18. doi: 10.1007/s00198-015-3342-4. Epub 2015 Oct 7. Osteoporos Int. 2016. PMID: 26446770 Free PMC article. Clinical Trial.

6

Ocular hypotensive effect of the novel EP3/FP agonist ONO-9054 versus Xalatan: results of a 28-day, double-masked, randomised study.

Miller Ellis E, Berlin MS, Ward CL, Sharpe JA, Jamil A, Harris A. Miller Ellis E, et al. Br J Ophthalmol. 2017 Jun;101(6):796-800. doi: 10.1136/bjophthalmol-2016-309023. Epub 2016 Sep 20. Br J Ophthalmol. 2017. PMID: 27649982 Free PMC article. Clinical Trial.

7

Bone turnover markers and pharmacokinetics of a new sustained-release formulation of the cathepsin K inhibitor, ONO-5334, in healthy post-menopausal women.

Nagase S, Ohyama M, Hashimoto Y, Small M, Sharpe J, Manako J, Kuwayama T, Deacon S. Nagase S, et al. Among authors: sharpe j. J Bone Miner Metab. 2015 Jan;33(1):93-100. doi: 10.1007/s00774-013-0558-2. Epub 2014 Jan 24. J Bone Miner Metab. 2015. PMID: 24458199 Clinical Trial.

8

Early autonomous patterning of the anteroposterior axis in gastruloids.

Anlaş K, Gritti N, Nakaki F, Salamó Palau L, Tlili SL, Oriola D, Arató K, Le Lim J, Sharpe J, Trivedi V. Anlaş K, et al. Among authors: sharpe j. Development. 2024 Nov 15;151(22):dev202171. doi: 10.1242/dev.202171. Epub 2024 Nov 18. Development. 2024. PMID: 39552366 Free PMC article.

9

A comparison of clinical and radiographic outcomes between isolated total talus replacement and combined total talus replacement with total ankle arthroplasty or hindfoot arthrodesis.

So E, Bala V, Sharpe J, Highlander P, Cottom J, McAlister J, Nowak J, Murdoch M. So E, et al. Among authors: sharpe j. J Foot Ankle Surg. 2024 Nov 12:S1067-2516(24)00247-3. doi: 10.1053/j.jfas.2024.10.001. Online ahead of print. J Foot Ankle Surg. 2024. PMID: 39537021

10

Wall-Eyed Internuclear Ophthalmoplegia: History and Hypothesis.

Johnston JL, Sharpe JA. Johnston JL, et al. Among authors: sharpe ja. Can J Neurol Sci. 2024 Nov 11:1-9. doi: 10.1017/cjn.2024.317. Online ahead of print. Can J Neurol Sci. 2024. PMID: 39523828

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