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Page 1
Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.
Li B, Giambelli C, Tang B, Winterbottom E, Long J, Jin K, Wang Z, Fei DL, Nguyen DM, Athar M, Wang B, Subbarayan PR, Wang L, Rai P, Ardalan B, Capobianco AJ, Robbins DJ. Li B, et al. Among authors: capobianco aj. Mol Pharmacol. 2016 Feb;89(2):226-32. doi: 10.1124/mol.115.100867. Epub 2015 Nov 16. Mol Pharmacol. 2016. PMID: 26573582 Free PMC article.
Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, Robbins DJ. Li B, et al. Among authors: capobianco aj. Cancer Res. 2014 Sep 1;74(17):4811-21. doi: 10.1158/0008-5472.CAN-14-0317. Epub 2014 Jul 3. Cancer Res. 2014. PMID: 24994715 Free PMC article.
GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth.
Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ. Winterbottom EF, et al. Among authors: capobianco aj. EBioMedicine. 2015 May 1;2(6):536-43. doi: 10.1016/j.ebiom.2015.04.019. eCollection 2015 Jun. EBioMedicine. 2015. PMID: 26288817 Free PMC article.
The hedgehog processing pathway is required for NSCLC growth and survival.
Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, Lam WL, Dmitrovsky E, Capobianco AJ, Robbins DJ. Rodriguez-Blanco J, et al. Among authors: capobianco aj. Oncogene. 2013 May 2;32(18):2335-45. doi: 10.1038/onc.2012.243. Epub 2012 Jun 25. Oncogene. 2013. PMID: 22733134 Free PMC article.
Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity.
Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Singh S, et al. Among authors: capobianco aj. Cancer Res. 2011 Jul 1;71(13):4454-63. doi: 10.1158/0008-5472.CAN-10-2313. Epub 2011 May 12. Cancer Res. 2011. PMID: 21565978 Free PMC article.
Hedgehog signaling regulates bladder cancer growth and tumorigenicity.
Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ. Fei DL, et al. Among authors: capobianco aj. Cancer Res. 2012 Sep 1;72(17):4449-58. doi: 10.1158/0008-5472.CAN-11-4123. Epub 2012 Jul 19. Cancer Res. 2012. PMID: 22815529 Free PMC article.
Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma.
Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, Sparling L, Pei XH, Franceschi D, Ribeiro A, Robbins DJ, Livingstone AS, Capobianco AJ. Wang Z, et al. Among authors: capobianco aj. Cancer Res. 2014 Nov 1;74(21):6364-74. doi: 10.1158/0008-5472.CAN-14-2051. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164006 Free PMC article.
Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex.
Han X, Ranganathan P, Tzimas C, Weaver KL, Jin K, Astudillo L, Zhou W, Zhu X, Li B, Robbins DJ, Capobianco AJ. Han X, et al. Among authors: capobianco aj. Mol Cancer Res. 2017 Sep;15(9):1173-1183. doi: 10.1158/1541-7786.MCR-17-0241. Epub 2017 Jun 5. Mol Cancer Res. 2017. PMID: 28584023 Free PMC article.
85 results