Poulsen A - Search Results

1

Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.

Pobbati AV, Han X, Hung AW, Weiguang S, Huda N, Chen GY, Kang C, Chia CS, Luo X, Hong W, Poulsen A. Pobbati AV, et al. Among authors: poulsen a. Structure. 2015 Nov 3;23(11):2076-86. doi: 10.1016/j.str.2015.09.009. Epub 2015 Oct 22. Structure. 2015. PMID: 26592798 Free PMC article.

2

Structural and ligand-binding analysis of the YAP-binding domain of transcription factor TEAD4.

Li Y, Liu S, Ng EY, Li R, Poulsen A, Hill J, Pobbati AV, Hung AW, Hong W, Keller TH, Kang C. Li Y, et al. Among authors: poulsen a. Biochem J. 2018 Jun 26;475(12):2043-2055. doi: 10.1042/BCJ20180225. Biochem J. 2018. PMID: 29760238

3

Drug design for flavivirus proteases: what are we missing?

Poulsen A, Kang C, Keller TH. Poulsen A, et al. Curr Pharm Des. 2014;20(21):3422-7. doi: 10.2174/13816128113199990633. Curr Pharm Des. 2014. PMID: 24001226 Review.

4

Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.

Liu BH, Jobichen C, Chia CSB, Chan THM, Tang JP, Chung TXY, Li J, Poulsen A, Hung AW, Koh-Stenta X, Tan YS, Verma CS, Tan HK, Wu CS, Li F, Hill J, Joy J, Yang H, Chai L, Sivaraman J, Tenen DG. Liu BH, et al. Among authors: poulsen a. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7119-E7128. doi: 10.1073/pnas.1801253115. Epub 2018 Jul 5. Proc Natl Acad Sci U S A. 2018. PMID: 29976840 Free PMC article.

5

Application of Fragment-Based Drug Discovery against DNA Gyrase B.

Chen GY, Ng FM, Tan YW, Poulsen A, Seetoh W, Lin G, Kang C, Then SW, Ahmad NH, Wong YL, Ng HQ, Chia CSB, Lau QY, Hill J, Hung AW, Keller TH. Chen GY, et al. Among authors: poulsen a. Chempluschem. 2015 Aug;80(8):1250-1254. doi: 10.1002/cplu.201500197. Epub 2015 Jun 24. Chempluschem. 2015. PMID: 31973307

6

Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: a P1-P4 SAR study.

Ang MJ, Yong GH, Poulsen A, Then SW, Li Z, Joy J, Hill J, Chia CS. Ang MJ, et al. Among authors: poulsen a. Eur J Med Chem. 2013 Oct;68:72-80. doi: 10.1016/j.ejmech.2013.07.028. Epub 2013 Aug 9. Eur J Med Chem. 2013. PMID: 23974013

7

Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors.

Kwiatkowski J, Liu B, Tee DHY, Chen G, Ahmad NHB, Wong YX, Poh ZY, Ang SH, Tan ESW, Ong EH, Nurul Dinie, Poulsen A, Pendharkar V, Sangthongpitag K, Lee MA, Sepramaniam S, Ho SY, Cherian J, Hill J, Keller TH, Hung AW. Kwiatkowski J, et al. Among authors: poulsen a. J Med Chem. 2018 May 24;61(10):4386-4396. doi: 10.1021/acs.jmedchem.8b00060. Epub 2018 May 4. J Med Chem. 2018. PMID: 29688013

8

Exploring the binding of peptidic West Nile virus NS2B-NS3 protease inhibitors by NMR.

Kang C, Gayen S, Wang W, Severin R, Chen AS, Lim HA, Chia CS, Schüller A, Doan DN, Poulsen A, Hill J, Vasudevan SG, Keller TH. Kang C, et al. Among authors: poulsen a. Antiviral Res. 2013 Feb;97(2):137-44. doi: 10.1016/j.antiviral.2012.11.008. Epub 2012 Dec 2. Antiviral Res. 2013. PMID: 23211132

9

Novel agmatine dipeptide inhibitors against the West Nile virus NS2B/NS3 protease: a P3 and N-cap optimization study.

Lim HA, Ang MJ, Joy J, Poulsen A, Wu W, Ching SC, Hill J, Chia CS. Lim HA, et al. Among authors: poulsen a. Eur J Med Chem. 2013 Apr;62:199-205. doi: 10.1016/j.ejmech.2012.12.043. Epub 2013 Jan 3. Eur J Med Chem. 2013. PMID: 23353753

10

Antiviral activities of peptide-based covalent inhibitors of the Enterovirus 71 3C protease.

Tan YW, Ang MJ, Lau QY, Poulsen A, Ng FM, Then SW, Peng J, Hill J, Hong WJ, Chia CS, Chu JJ. Tan YW, et al. Among authors: poulsen a. Sci Rep. 2016 Sep 20;6:33663. doi: 10.1038/srep33663. Sci Rep. 2016. PMID: 27645381 Free PMC article.

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