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β2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis.
Oellerich T, Oellerich MF, Engelke M, Münch S, Mohr S, Nimz M, Hsiao HH, Corso J, Zhang J, Bohnenberger H, Berg T, Rieger MA, Wienands J, Bug G, Brandts C, Urlaub H, Serve H. Oellerich T, et al. Among authors: bohnenberger h. Blood. 2013 May 9;121(19):3889-99, S1-66. doi: 10.1182/blood-2012-09-457887. Epub 2013 Mar 18. Blood. 2013. PMID: 23509157 Free article.
FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation.
Oellerich T, Mohr S, Corso J, Beck J, Döbele C, Braun H, Cremer A, Münch S, Wicht J, Oellerich MF, Bug G, Bohnenberger H, Perske C, Schütz E, Urlaub H, Serve H. Oellerich T, et al. Among authors: bohnenberger h. Blood. 2015 Mar 19;125(12):1936-47. doi: 10.1182/blood-2014-06-585216. Epub 2015 Jan 20. Blood. 2015. PMID: 25605370 Free article.
Elucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival.
Corso J, Pan KT, Walter R, Doebele C, Mohr S, Bohnenberger H, Ströbel P, Lenz C, Slabicki M, Hüllein J, Comoglio F, Rieger MA, Zenz T, Wienands J, Engelke M, Serve H, Urlaub H, Oellerich T. Corso J, et al. Among authors: bohnenberger h. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5688-93. doi: 10.1073/pnas.1601053113. Epub 2016 May 6. Proc Natl Acad Sci U S A. 2016. PMID: 27155012 Free PMC article.
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
Schneider C, Oellerich T, Baldauf HM, Schwarz SM, Thomas D, Flick R, Bohnenberger H, Kaderali L, Stegmann L, Cremer A, Martin M, Lohmeyer J, Michaelis M, Hornung V, Schliemann C, Berdel WE, Hartmann W, Wardelmann E, Comoglio F, Hansmann ML, Yakunin AF, Geisslinger G, Ströbel P, Ferreirós N, Serve H, Keppler OT, Cinatl J Jr. Schneider C, et al. Among authors: bohnenberger h. Nat Med. 2017 Feb;23(2):250-255. doi: 10.1038/nm.4255. Epub 2016 Dec 19. Nat Med. 2017. PMID: 27991919
HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling.
Walter R, Pan KT, Doebele C, Comoglio F, Tomska K, Bohnenberger H, Young RM, Jacobs L, Keller U, Bönig H, Engelke M, Rosenwald A, Urlaub H, Staudt LM, Serve H, Zenz T, Oellerich T. Walter R, et al. Among authors: bohnenberger h. Blood. 2017 Feb 2;129(5):598-608. doi: 10.1182/blood-2016-06-721423. Epub 2016 Nov 15. Blood. 2017. PMID: 28064214 Free PMC article.
102 results