Grosse-Hovest L - Search Results

1

A Humanized Anti-CD22-Onconase Antibody-Drug Conjugate Mediates Highly Potent Destruction of Targeted Tumor Cells.

Weber T, Mavratzas A, Kiesgen S, Haase S, Bötticher B, Exner E, Mier W, Grosse-Hovest L, Jäger D, Arndt MA, Krauss J. Weber T, et al. Among authors: grosse hovest l. J Immunol Res. 2015;2015:561814. doi: 10.1155/2015/561814. Epub 2015 Oct 28. J Immunol Res. 2015. PMID: 26605343 Free PMC article.

2

A recombinant bispecific single-chain antibody induces targeted, supra-agonistic CD28-stimulation and tumor cell killing.

Grosse-Hovest L, Hartlapp I, Marwan W, Brem G, Rammensee HG, Jung G. Grosse-Hovest L, et al. Eur J Immunol. 2003 May;33(5):1334-40. doi: 10.1002/eji.200323322. Eur J Immunol. 2003. PMID: 12731059 Free article.

3

Overcoming drug-resistant herpes simplex virus (HSV) infection by a humanized antibody.

Krawczyk A, Arndt MA, Grosse-Hovest L, Weichert W, Giebel B, Dittmer U, Hengel H, Jäger D, Schneweis KE, Eis-Hübinger AM, Roggendorf M, Krauss J. Krawczyk A, et al. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6760-5. doi: 10.1073/pnas.1220019110. Epub 2013 Apr 8. Proc Natl Acad Sci U S A. 2013. PMID: 23569258 Free PMC article.

4

Fc-optimized NKG2D-Fc constructs induce NK cell antibody-dependent cellular cytotoxicity against breast cancer cells independently of HER2/neu expression status.

Raab S, Steinbacher J, Schmiedel BJ, Kousis PC, Steinle A, Jung G, Grosse-Hovest L, Salih HR. Raab S, et al. J Immunol. 2014 Oct 15;193(8):4261-72. doi: 10.4049/jimmunol.1400872. Epub 2014 Sep 12. J Immunol. 2014. PMID: 25217158

5

High treatment efficacy by dual targeting of Burkitt's lymphoma xenografted mice with a (177)Lu-based CD22-specific radioimmunoconjugate and rituximab.

Weber T, Bötticher B, Mier W, Sauter M, Krämer S, Leotta K, Keller A, Schlegelmilch A, Grosse-Hovest L, Jäger D, Haberkorn U, Arndt MA, Krauss J. Weber T, et al. Eur J Nucl Med Mol Imaging. 2016 Mar;43(3):489-98. doi: 10.1007/s00259-015-3175-6. Epub 2015 Sep 4. Eur J Nucl Med Mol Imaging. 2016. PMID: 26341366

6

Preclinical evaluation of a diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy in a non-Hodgkin lymphoma mouse model.

Weber T, Bötticher B, Arndt MA, Mier W, Sauter M, Exner E, Keller A, Krämer S, Leotta K, Wischnjow A, Grosse-Hovest L, Strumberg D, Jäger D, Gröne HJ, Haberkorn U, Brem G, Krauss J. Weber T, et al. Among authors: grosse hovest l. Cancer Lett. 2016 Oct 28;381(2):296-304. doi: 10.1016/j.canlet.2016.08.007. Epub 2016 Aug 11. Cancer Lett. 2016. PMID: 27524505

7

Construction of optimized bispecific antibodies for selective activation of the death receptor CD95.

Herrmann T, Grosse-Hovest L, Otz T, Krammer PH, Rammensee HG, Jung G. Herrmann T, et al. Cancer Res. 2008 Feb 15;68(4):1221-7. doi: 10.1158/0008-5472.CAN-07-6175. Cancer Res. 2008. PMID: 18281499

8

A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells.

Otz T, Grosse-Hovest L, Hofmann M, Rammensee HG, Jung G. Otz T, et al. Leukemia. 2009 Jan;23(1):71-7. doi: 10.1038/leu.2008.271. Epub 2008 Oct 2. Leukemia. 2009. PMID: 18830257

9

Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia.

Hofmann M, Große-Hovest L, Nübling T, Pyż E, Bamberg ML, Aulwurm S, Bühring HJ, Schwartz K, Haen SP, Schilbach K, Rammensee HG, Salih HR, Jung G. Hofmann M, et al. Leukemia. 2012 Jun;26(6):1228-37. doi: 10.1038/leu.2011.372. Epub 2012 Jan 6. Leukemia. 2012. PMID: 22289926

10

Comprehensive analysis of NKG2D ligand expression and release in leukemia: implications for NKG2D-mediated NK cell responses.

Hilpert J, Grosse-Hovest L, Grünebach F, Buechele C, Nuebling T, Raum T, Steinle A, Salih HR. Hilpert J, et al. J Immunol. 2012 Aug 1;189(3):1360-71. doi: 10.4049/jimmunol.1200796. Epub 2012 Jun 22. J Immunol. 2012. PMID: 22730533

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