Gaedigk A - Search Results

1

Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation.

Pearce RE, Gaedigk R, Twist GP, Dai H, Riffel AK, Leeder JS, Gaedigk A. Pearce RE, et al. Among authors: gaedigk a, gaedigk r. Drug Metab Dispos. 2016 Jul;44(7):948-58. doi: 10.1124/dmd.115.067546. Epub 2015 Nov 25. Drug Metab Dispos. 2016. PMID: 26608082 Free PMC article.

2

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism.

Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. Gaedigk A, et al. Among authors: gaedigk r. Am J Hum Genet. 1991 May;48(5):943-50. Am J Hum Genet. 1991. PMID: 1673290 Free PMC article.

3

Epitope mapping studies with human anti-cytochrome P450 3A antibodies.

Leeder JS, Gaedigk A, Lu X, Cook VA. Leeder JS, et al. Among authors: gaedigk a. Mol Pharmacol. 1996 Feb;49(2):234-43. Mol Pharmacol. 1996. PMID: 8632755

4

Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase.

Gaedigk A, Leeder JS, Grant DM. Gaedigk A, et al. DNA Cell Biol. 1997 Nov;16(11):1257-66. doi: 10.1089/dna.1997.16.1257. DNA Cell Biol. 1997. PMID: 9406998

5

Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions.

Leeder JS, Lu X, Timsit Y, Gaedigk A. Leeder JS, et al. Among authors: gaedigk a. Pharmacogenetics. 1998 Jun;8(3):211-25. doi: 10.1097/00008571-199806000-00004. Pharmacogenetics. 1998. PMID: 9682267

6

NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations.

Gaedigk A, Tyndale RF, Jurima-Romet M, Sellers EM, Grant DM, Leeder JS. Gaedigk A, et al. Pharmacogenetics. 1998 Aug;8(4):305-13. doi: 10.1097/00008571-199808000-00004. Pharmacogenetics. 1998. PMID: 9731717

7

Quantification of intraindividual variability and the influence of menstrual cycle phase on CYP2D6 activity as measured by dextromethorphan phenotyping.

Kashuba AD, Nafziger AN, Kearns GL, Leeder JS, Shirey CS, Gotschall R, Gaedigk A, Bertino JS Jr. Kashuba AD, et al. Among authors: gaedigk a. Pharmacogenetics. 1998 Oct;8(5):403-10. doi: 10.1097/00008571-199810000-00005. Pharmacogenetics. 1998. PMID: 9825832

8

High frequency of CYP2D6 poor and "intermediate" metabolizers in black populations: a review and preliminary data.

Bradford LD, Gaedigk A, Leeder JS. Bradford LD, et al. Among authors: gaedigk a. Psychopharmacol Bull. 1998;34(4):797-804. Psychopharmacol Bull. 1998. PMID: 10513455 Review.

9

Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.

Streetman DS, Ellis RE, Nafziger AN, Leeder JS, Gaedigk A, Gotschall R, Kearns GL, Bertino JS Jr. Streetman DS, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 1999 Nov;66(5):535-41. doi: 10.1016/S0009-9236(99)70018-4. Clin Pharmacol Ther. 1999. PMID: 10579482 Clinical Trial.

10

Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.

Gaedigk A, Gotschall RR, Forbes NS, Simon SD, Kearns GL, Leeder JS. Gaedigk A, et al. Pharmacogenetics. 1999 Dec;9(6):669-82. doi: 10.1097/01213011-199912000-00002. Pharmacogenetics. 1999. PMID: 10634130

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