Chaudhary D - Search Results

1

Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy.

Kelly PN, Romero DL, Yang Y, Shaffer AL 3rd, Chaudhary D, Robinson S, Miao W, Rui L, Westlin WF, Kapeller R, Staudt LM. Kelly PN, et al. Among authors: chaudhary d. J Exp Med. 2015 Dec 14;212(13):2189-201. doi: 10.1084/jem.20151074. Epub 2015 Nov 30. J Exp Med. 2015. PMID: 26621451 Free PMC article.

2

Recent advances in the discovery of small molecule inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4) as a therapeutic target for inflammation and oncology disorders.

Chaudhary D, Robinson S, Romero DL. Chaudhary D, et al. J Med Chem. 2015 Jan 8;58(1):96-110. doi: 10.1021/jm5016044. Epub 2014 Dec 5. J Med Chem. 2015. PMID: 25479567 Review.

3

MYD88 L265P mutations identify a prognostic gene expression signature and a pathway for targeted inhibition in CLL.

Improgo MR, Tesar B, Klitgaard JL, Magori-Cohen R, Yu L, Kasar S, Chaudhary D, Miao W, Fernandes SM, Hoang K, Westlin WF, Kim HT, Brown JR. Improgo MR, et al. Among authors: chaudhary d. Br J Haematol. 2019 Mar;184(6):925-936. doi: 10.1111/bjh.15714. Epub 2018 Dec 9. Br J Haematol. 2019. PMID: 30537114 Free article.

4

PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta.

Sheppard KA, Fitz LJ, Lee JM, Benander C, George JA, Wooters J, Qiu Y, Jussif JM, Carter LL, Wood CR, Chaudhary D. Sheppard KA, et al. Among authors: chaudhary d. FEBS Lett. 2004 Sep 10;574(1-3):37-41. doi: 10.1016/j.febslet.2004.07.083. FEBS Lett. 2004. PMID: 15358536 Free article.

5

PKCtheta: A potential therapeutic target for T-cell-mediated diseases.

Chaudhary D, Kasaian M. Chaudhary D, et al. Curr Opin Investig Drugs. 2006 May;7(5):432-7. Curr Opin Investig Drugs. 2006. PMID: 16729719 Review.

6

Structure-based optimization of PKCtheta inhibitors.

Mosyak L, Xu Z, Joseph-McCarthy D, Brooijmans N, Somers W, Chaudhary D. Mosyak L, et al. Among authors: chaudhary d. Biochem Soc Trans. 2007 Nov;35(Pt 5):1027-31. doi: 10.1042/BST0351027. Biochem Soc Trans. 2007. PMID: 17956269 Review.

7

IL-33 synergizes with IgE-dependent and IgE-independent agents to promote mast cell and basophil activation.

Silver MR, Margulis A, Wood N, Goldman SJ, Kasaian M, Chaudhary D. Silver MR, et al. Among authors: chaudhary d. Inflamm Res. 2010 Mar;59(3):207-18. doi: 10.1007/s00011-009-0088-5. Epub 2009 Sep 18. Inflamm Res. 2010. PMID: 19763788

8

Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.

Boschelli DH, Subrath J, Niu C, Wu B, Wang Y, Lee J, Brennan A, Ho M, Deng B, Yang X, Xu X, Leung L, Wang J, Atherton J, Chaudhary D. Boschelli DH, et al. Among authors: chaudhary d. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1965-8. doi: 10.1016/j.bmcl.2010.01.119. Epub 2010 Jan 28. Bioorg Med Chem Lett. 2010. PMID: 20153643

9

Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma.

Krane CM, Deng B, Mutyam V, McDonald CA, Pazdziorko S, Mason L, Goldman S, Kasaian M, Chaudhary D, Williams C, Ho MW. Krane CM, et al. Among authors: chaudhary d. Cytokine. 2009 Apr;46(1):111-8. doi: 10.1016/j.cyto.2008.12.018. Epub 2009 Feb 23. Cytokine. 2009. PMID: 19237298 Free PMC article.

10

Natural killer cells from protein kinase C theta-/- mice stimulated with interleukin-12 are deficient in production of interferon-gamma.

Page KM, Chaudhary D, Goldman SJ, Kasaian MT. Page KM, et al. Among authors: chaudhary d. J Leukoc Biol. 2008 May;83(5):1267-76. doi: 10.1189/jlb.1107745. Epub 2008 Feb 8. J Leukoc Biol. 2008. PMID: 18263766

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