Wrana J - Search Results

1

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism.

Rotin LE, Gronda M, MacLean N, Hurren R, Wang X, Lin FH, Wrana J, Datti A, Barber DL, Minden MD, Slassi M, Schimmer AD. Rotin LE, et al. Among authors: wrana j. Oncotarget. 2016 Jan 19;7(3):2765-79. doi: 10.18632/oncotarget.6409. Oncotarget. 2016. PMID: 26624983 Free PMC article.

2

A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis.

Mawji IA, Simpson CD, Gronda M, Williams MA, Hurren R, Henderson CJ, Datti A, Wrana JL, Schimmer AD. Mawji IA, et al. Among authors: wrana jl. Cancer Res. 2007 Sep 1;67(17):8307-15. doi: 10.1158/0008-5472.CAN-07-1687. Cancer Res. 2007. PMID: 17804746 Free article.

3

A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin.

Mao X, Stewart AK, Hurren R, Datti A, Zhu X, Zhu Y, Shi C, Lee K, Tiedemann R, Eberhard Y, Trudel S, Liang S, Corey SJ, Gillis LC, Barber DL, Wrana JL, Ezzat S, Schimmer AD. Mao X, et al. Among authors: wrana jl. Blood. 2007 Dec 1;110(12):4047-54. doi: 10.1182/blood-2007-05-088666. Epub 2007 Sep 17. Blood. 2007. PMID: 17875808 Free article.

4

A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization.

Xu GW, Mawji IA, Macrae CJ, Koch CA, Datti A, Wrana JL, Dennis JW, Schimmer AD. Xu GW, et al. Among authors: wrana jl. Apoptosis. 2008 Mar;13(3):413-22. doi: 10.1007/s10495-007-0175-4. Apoptosis. 2008. PMID: 18181020

5

Cyproheptadine displays preclinical activity in myeloma and leukemia.

Mao X, Liang SB, Hurren R, Gronda M, Chow S, Xu GW, Wang X, Beheshti Zavareh R, Jamal N, Messner H, Hedley DW, Datti A, Wrana JL, Zhu Y, Shi CX, Lee K, Tiedemann R, Trudel S, Stewart AK, Schimmer AD. Mao X, et al. Blood. 2008 Aug 1;112(3):760-9. doi: 10.1182/blood-2008-02-142687. Epub 2008 May 23. Blood. 2008. PMID: 18502826 Free article.

6

Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function.

Beheshti Zavareh R, Lau KS, Hurren R, Datti A, Ashline DJ, Gronda M, Cheung P, Simpson CD, Liu W, Wasylishen AR, Boutros PC, Shi H, Vengopal A, Jurisica I, Penn LZ, Reinhold VN, Ezzat S, Wrana J, Rose DR, Schachter H, Dennis JW, Schimmer AD. Beheshti Zavareh R, et al. Among authors: wrana j. Cancer Res. 2008 Aug 15;68(16):6688-97. doi: 10.1158/0008-5472.CAN-07-6833. Cancer Res. 2008. PMID: 18701493

7

Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation.

Simpson CD, Mawji IA, Anyiwe K, Williams MA, Wang X, Venugopal AL, Gronda M, Hurren R, Cheng S, Serra S, Beheshti Zavareh R, Datti A, Wrana JL, Ezzat S, Schimmer AD. Simpson CD, et al. Cancer Res. 2009 Apr 1;69(7):2739-47. doi: 10.1158/0008-5472.CAN-08-2530. Epub 2009 Mar 17. Cancer Res. 2009. PMID: 19293189

8

Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.

Eberhard Y, McDermott SP, Wang X, Gronda M, Venugopal A, Wood TE, Hurren R, Datti A, Batey RA, Wrana J, Antholine WE, Dick JE, Schimmer AD. Eberhard Y, et al. Among authors: wrana j. Blood. 2009 Oct 1;114(14):3064-73. doi: 10.1182/blood-2009-03-209965. Epub 2009 Jul 9. Blood. 2009. PMID: 19589922 Free article.

9

Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway.

Miller BW, Lau G, Grouios C, Mollica E, Barrios-Rodiles M, Liu Y, Datti A, Morris Q, Wrana JL, Attisano L. Miller BW, et al. Mol Syst Biol. 2009;5:315. doi: 10.1038/msb.2009.72. Epub 2009 Oct 13. Mol Syst Biol. 2009. PMID: 19888210 Free PMC article.

10

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL. Samavarchi-Tehrani P, et al. Cell Stem Cell. 2010 Jul 2;7(1):64-77. doi: 10.1016/j.stem.2010.04.015. Epub 2010 Jun 17. Cell Stem Cell. 2010. PMID: 20621051 Free article.

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