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An update on the current pharmacotherapy for endometrial cancer.
de Haydu C, Black JD, Schwab CL, English DP, Santin AD. de Haydu C, et al. Among authors: black jd. Expert Opin Pharmacother. 2016;17(4):489-99. doi: 10.1517/14656566.2016.1127351. Epub 2015 Dec 23. Expert Opin Pharmacother. 2016. PMID: 26629895 Review.
Dacomitinib (PF-00299804), a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor, demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro.
Zhu L, Lopez S, Bellone S, Black J, Cocco E, Zigras T, Predolini F, Bonazzoli E, Bussi B, Stuhmer Z, Schwab CL, English DP, Ratner E, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Santin AD. Zhu L, et al. Tumour Biol. 2015 Jul;36(7):5505-13. doi: 10.1007/s13277-015-3218-4. Epub 2015 Feb 11. Tumour Biol. 2015. PMID: 25669172 Free PMC article.
Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE), is highly active against primary uterine serous papillary carcinoma cell lines in vitro.
Bellone S, Black J, English DP, Schwab CL, Lopez S, Cocco E, Bonazzoli E, Predolini F, Ferrari F, Ratner E, Silasi DA, Azodi M, Schwartz PE, Santin AD. Bellone S, et al. Am J Obstet Gynecol. 2016 Jan;214(1):99.e1-8. doi: 10.1016/j.ajog.2015.08.011. Epub 2015 Aug 10. Am J Obstet Gynecol. 2016. PMID: 26272866 Free PMC article.
179 results