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Human β-Defensin 3 [corrected] Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid.
Semple F, MacPherson H, Webb S, Kilanowski F, Lettice L, McGlasson SL, Wheeler AP, Chen V, Millhauser GL, Melrose L, Davidson DJ, Dorin JR. Semple F, et al. Among authors: melrose l. PLoS Genet. 2015 Dec 8;11(12):e1005673. doi: 10.1371/journal.pgen.1005673. eCollection 2015 Dec. PLoS Genet. 2015. PMID: 26646717 Free PMC article.
Correction: Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid.
Semple F, MacPherson H, Webb S, Kilanowski F, Lettice L, McGlasson SL, Wheeler AP, Chen V, Millhauser GL, Melrose L, Davidson DJ, Dorin JR. Semple F, et al. Among authors: melrose l. PLoS Genet. 2016 Jan 8;12(1):e1005801. doi: 10.1371/journal.pgen.1005801. eCollection 2016 Jan. PLoS Genet. 2016. PMID: 26744891 Free PMC article.
The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation.
Smith KJ, Minns D, McHugh BJ, Holloway RK, O'Connor R, Williams A, Melrose L, McPherson R, Miron VE, Davidson DJ, Gwyer Findlay E. Smith KJ, et al. Among authors: melrose l. PLoS Biol. 2022 Aug 26;20(8):e3001554. doi: 10.1371/journal.pbio.3001554. eCollection 2022 Aug. PLoS Biol. 2022. PMID: 36026478 Free PMC article.
Nasal cathelicidin is expressed in early life and is increased during mild, but not severe respiratory syncytial virus infection.
Sintoris S, Binkowska JM, Gillan JL, Zuurbier RP, Twynam-Perkins J, Kristensen M, Melrose L, Parga PL, Rodriguez AR, Chu ML, van Boeckel SR, Wildenbeest JG, Bowdish DME, Currie AJ, Thwaites RS, Schwarze J, van Houten MA, Boardman JP, Cunningham S, Bogaert D, Davidson DJ. Sintoris S, et al. Among authors: melrose l. Sci Rep. 2024 Jun 17;14(1):13928. doi: 10.1038/s41598-024-64446-1. Sci Rep. 2024. PMID: 38886476 Free PMC article.