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LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.
Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T, Rieser E, Martino L, Rittinger K, Walczak H. Draber P, et al. Among authors: rittinger k. Cell Rep. 2015 Dec 15;13(10):2258-72. doi: 10.1016/j.celrep.2015.11.009. Epub 2015 Dec 6. Cell Rep. 2015. PMID: 26670046 Free PMC article.
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate.
Stieglitz B, Morris-Davies AC, Koliopoulos MG, Christodoulou E, Rittinger K. Stieglitz B, et al. Among authors: rittinger k. EMBO Rep. 2012 Sep;13(9):840-6. doi: 10.1038/embor.2012.105. Epub 2012 Jul 13. EMBO Rep. 2012. PMID: 22791023 Free PMC article.
97 results