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LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.
Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T, Rieser E, Martino L, Rittinger K, Walczak H. Draber P, et al. Among authors: de miguel d. Cell Rep. 2015 Dec 15;13(10):2258-72. doi: 10.1016/j.celrep.2015.11.009. Epub 2015 Dec 6. Cell Rep. 2015. PMID: 26670046 Free PMC article.
Onto better TRAILs for cancer treatment.
de Miguel D, Lemke J, Anel A, Walczak H, Martinez-Lostao L. de Miguel D, et al. Cell Death Differ. 2016 May;23(5):733-47. doi: 10.1038/cdd.2015.174. Epub 2016 Mar 4. Cell Death Differ. 2016. PMID: 26943322 Free PMC article. Review.
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.
Lafont E, Draber P, Rieser E, Reichert M, Kupka S, de Miguel D, Draberova H, von Mässenhausen A, Bhamra A, Henderson S, Wojdyla K, Chalk A, Surinova S, Linkermann A, Walczak H. Lafont E, et al. Among authors: de miguel d. Nat Cell Biol. 2018 Dec;20(12):1389-1399. doi: 10.1038/s41556-018-0229-6. Epub 2018 Nov 12. Nat Cell Biol. 2018. PMID: 30420664 Free PMC article.
Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair.
Martinez Lagunas K, Savcigil DP, Zrilic M, Carvajal Fraile C, Craxton A, Self E, Uranga-Murillo I, de Miguel D, Arias M, Willenborg S, Piekarek M, Albert MC, Nugraha K, Lisewski I, Janakova E, Igual N, Tonnus W, Hildebrandt X, Ibrahim M, Ballegeer M, Saelens X, Kueh A, Meier P, Linkermann A, Pardo J, Eming S, Walczak H, MacFarlane M, Peltzer N, Annibaldi A. Martinez Lagunas K, et al. Among authors: de miguel d. Sci Adv. 2023 Jul 28;9(30):eadg2829. doi: 10.1126/sciadv.adg2829. Epub 2023 Jul 26. Sci Adv. 2023. PMID: 37494451 Free PMC article.
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
Albert MC, Uranga-Murillo I, Arias M, De Miguel D, Peña N, Montinaro A, Varanda AB, Theobald SJ, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado-Guerrero R, Merino P, Monzón M, Badiola JJ, Reindl-Schwaighofer R, Sanz-Pamplona R, Cebollada-Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo J, Walczak H. Albert MC, et al. Among authors: de miguel d. Cell Death Differ. 2024 May;31(5):544-557. doi: 10.1038/s41418-024-01278-6. Epub 2024 Mar 21. Cell Death Differ. 2024. PMID: 38514848 Free PMC article.
Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.
Jaime-Sánchez P, Catalán E, Uranga-Murillo I, Aguiló N, Santiago L, M Lanuza P, de Miguel D, A Arias M, Pardo J. Jaime-Sánchez P, et al. Among authors: de miguel d. Cell Death Differ. 2018 Sep;25(9):1536-1548. doi: 10.1038/s41418-018-0112-9. Epub 2018 May 9. Cell Death Differ. 2018. PMID: 29743559 Free PMC article.
82 results