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APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.
Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S 3rd, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR. Olabisi OA, et al. Among authors: yan p. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):830-7. doi: 10.1073/pnas.1522913113. Epub 2015 Dec 23. Proc Natl Acad Sci U S A. 2016. PMID: 26699492 Free PMC article.
UBD modifies APOL1-induced kidney disease risk.
Zhang JY, Wang M, Tian L, Genovese G, Yan P, Wilson JG, Thadhani R, Mottl AK, Appel GB, Bick AG, Sampson MG, Alper SL, Friedman DJ, Pollak MR. Zhang JY, et al. Among authors: yan p. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3446-3451. doi: 10.1073/pnas.1716113115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531077 Free PMC article.
FSGS-Causing INF2 Mutation Impairs Cleaved INF2 N-Fragment Functions in Podocytes.
Subramanian B, Chun J, Perez-Gill C, Yan P, Stillman IE, Higgs HN, Alper SL, Schlöndorff JS, Pollak MR. Subramanian B, et al. Among authors: yan p. J Am Soc Nephrol. 2020 Feb;31(2):374-391. doi: 10.1681/ASN.2019050443. Epub 2020 Jan 10. J Am Soc Nephrol. 2020. PMID: 31924668 Free PMC article.
3,701 results