Hancock REW - Search Results

1

Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities.

Bionda N, Fleeman RM, de la Fuente-Núñez C, Rodriguez MC, Reffuveille F, Shaw LN, Pastar I, Davis SC, Hancock REW, Cudic P. Bionda N, et al. Among authors: hancock rew. Eur J Med Chem. 2016 Jan 27;108:354-363. doi: 10.1016/j.ejmech.2015.11.032. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26703794 Free PMC article.

2

High-throughput generation of small antibacterial peptides with improved activity.

Hilpert K, Volkmer-Engert R, Walter T, Hancock RE. Hilpert K, et al. Nat Biotechnol. 2005 Aug;23(8):1008-12. doi: 10.1038/nbt1113. Epub 2005 Jul 24. Nat Biotechnol. 2005. PMID: 16041366 Free article.

3

Sequence requirements and an optimization strategy for short antimicrobial peptides.

Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE. Hilpert K, et al. Chem Biol. 2006 Oct;13(10):1101-7. doi: 10.1016/j.chembiol.2006.08.014. Chem Biol. 2006. PMID: 17052614

4

Use of luminescent bacteria for rapid screening and characterization of short cationic antimicrobial peptides synthesized on cellulose using peptide array technology.

Hilpert K, Hancock RE. Hilpert K, et al. Nat Protoc. 2007;2(7):1652-60. doi: 10.1038/nprot.2007.203. Nat Protoc. 2007. PMID: 17641630

5

QSAR modeling and computer-aided design of antimicrobial peptides.

Jenssen H, Fjell CD, Cherkasov A, Hancock RE. Jenssen H, et al. J Pept Sci. 2008 Jan;14(1):110-4. doi: 10.1002/psc.908. J Pept Sci. 2008. PMID: 17847019

6

Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs.

Cherkasov A, Hilpert K, Jenssen H, Fjell CD, Waldbrook M, Mullaly SC, Volkmer R, Hancock RE. Cherkasov A, et al. ACS Chem Biol. 2009 Jan 16;4(1):65-74. doi: 10.1021/cb800240j. ACS Chem Biol. 2009. PMID: 19055425

7

Screening and characterization of surface-tethered cationic peptides for antimicrobial activity.

Hilpert K, Elliott M, Jenssen H, Kindrachuk J, Fjell CD, Körner J, Winkler DF, Weaver LL, Henklein P, Ulrich AS, Chiang SH, Farmer SW, Pante N, Volkmer R, Hancock RE. Hilpert K, et al. Chem Biol. 2009 Jan 30;16(1):58-69. doi: 10.1016/j.chembiol.2008.11.006. Chem Biol. 2009. PMID: 19171306

8

Identification of novel antibacterial peptides by chemoinformatics and machine learning.

Fjell CD, Jenssen H, Hilpert K, Cheung WA, Panté N, Hancock RE, Cherkasov A. Fjell CD, et al. J Med Chem. 2009 Apr 9;52(7):2006-15. doi: 10.1021/jm8015365. J Med Chem. 2009. PMID: 19296598

9

Strategies for the discovery and advancement of novel cationic antimicrobial peptides.

Hadley EB, Hancock RE. Hadley EB, et al. Curr Top Med Chem. 2010;10(18):1872-81. doi: 10.2174/156802610793176648. Curr Top Med Chem. 2010. PMID: 20615190 Review.

10

Structural studies of a peptide with immune modulating and direct antimicrobial activity.

Wieczorek M, Jenssen H, Kindrachuk J, Scott WR, Elliott M, Hilpert K, Cheng JT, Hancock RE, Straus SK. Wieczorek M, et al. Chem Biol. 2010 Sep 24;17(9):970-80. doi: 10.1016/j.chembiol.2010.07.007. Chem Biol. 2010. PMID: 20851346

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