Dai HM - Search Results

1

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.

Zhu Y, Tchkonia T, Fuhrmann-Stroissnigg H, Dai HM, Ling YY, Stout MB, Pirtskhalava T, Giorgadze N, Johnson KO, Giles CB, Wren JD, Niedernhofer LJ, Robbins PD, Kirkland JL. Zhu Y, et al. Among authors: dai hm. Aging Cell. 2016 Jun;15(3):428-35. doi: 10.1111/acel.12445. Epub 2016 Mar 18. Aging Cell. 2016. PMID: 26711051 Free PMC article.

2

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.

Dai H, Smith A, Meng XW, Schneider PA, Pang YP, Kaufmann SH. Dai H, et al. J Cell Biol. 2011 Jul 11;194(1):39-48. doi: 10.1083/jcb.201102027. Epub 2011 Jul 4. J Cell Biol. 2011. PMID: 21727192 Free PMC article.

3

MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors.

Knorr KL, Schneider PA, Meng XW, Dai H, Smith BD, Hess AD, Karp JE, Kaufmann SH. Knorr KL, et al. Cell Death Differ. 2015 Dec;22(12):2133-42. doi: 10.1038/cdd.2015.74. Epub 2015 Jun 5. Cell Death Differ. 2015. PMID: 26045051 Free PMC article.

4

Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis.

Dai H, Meng XW, Lee SH, Schneider PA, Kaufmann SH. Dai H, et al. J Biol Chem. 2009 Jul 3;284(27):18311-22. doi: 10.1074/jbc.M109.004770. Epub 2009 Apr 7. J Biol Chem. 2009. PMID: 19351886 Free PMC article.

5

Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cells.

Smith AJ, Dai H, Correia C, Takahashi R, Lee SH, Schmitz I, Kaufmann SH. Smith AJ, et al. J Biol Chem. 2011 May 20;286(20):17682-92. doi: 10.1074/jbc.M110.189092. Epub 2011 Mar 22. J Biol Chem. 2011. PMID: 21454712 Free PMC article.

6

CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak.

Kremer KN, Peterson KL, Schneider PA, Meng XW, Dai H, Hess AD, Smith BD, Rodriguez-Ramirez C, Karp JE, Kaufmann SH, Hedin KE. Kremer KN, et al. J Biol Chem. 2013 Aug 9;288(32):22899-914. doi: 10.1074/jbc.M113.449926. Epub 2013 Jun 24. J Biol Chem. 2013. PMID: 23798675 Free PMC article. Clinical Trial.

7

Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance.

Dai H, Ding H, Meng XW, Lee SH, Schneider PA, Kaufmann SH. Dai H, et al. Cancer Res. 2013 Dec 1;73(23):6998-7008. doi: 10.1158/0008-5472.CAN-13-0940. Epub 2013 Oct 4. Cancer Res. 2013. PMID: 24097825 Free PMC article.

8

Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis.

Ilyas SI, Mertens JC, Bronk SF, Hirsova P, Dai H, Roberts LR, Kaufmann SH, Gores GJ. Ilyas SI, et al. J Biol Chem. 2014 Aug 15;289(33):22835-22849. doi: 10.1074/jbc.M114.563064. Epub 2014 Jun 27. J Biol Chem. 2014. PMID: 24973208 Free PMC article.

9

Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.

Correia C, Lee SH, Meng XW, Vincelette ND, Knorr KL, Ding H, Nowakowski GS, Dai H, Kaufmann SH. Correia C, et al. Biochim Biophys Acta. 2015 Jul;1853(7):1658-71. doi: 10.1016/j.bbamcr.2015.03.012. Epub 2015 Mar 27. Biochim Biophys Acta. 2015. PMID: 25827952 Free PMC article. Review.

10

Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells.

Dai H, Ding H, Meng XW, Peterson KL, Schneider PA, Karp JE, Kaufmann SH. Dai H, et al. Genes Dev. 2015 Oct 15;29(20):2140-52. doi: 10.1101/gad.267997.115. Genes Dev. 2015. PMID: 26494789 Free PMC article.

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