Sinko PJ - Search Results

1

Colorectal delivery and retention of PEG-Amprenavir-Bac7 nanoconjugates--proof of concept for HIV mucosal pre-exposure prophylaxis.

Samizadeh M, Zhang X, Gunaseelan S, Nelson AG, Palombo MS, Myers DR, Singh Y, Ganapathi U, Szekely Z, Sinko PJ. Samizadeh M, et al. Among authors: sinko pj. Drug Deliv Transl Res. 2016 Feb;6(1):1-16. doi: 10.1007/s13346-015-0269-4. Drug Deliv Transl Res. 2016. PMID: 26712122 Free PMC article.

2

Synthesis of poly(ethylene glycol)-based saquinavir prodrug conjugates and assessment of release and anti-HIV-1 bioactivity using a novel protease inhibition assay.

Gunaseelan S, Debrah O, Wan L, Leibowitz MJ, Rabson AB, Stein S, Sinko PJ. Gunaseelan S, et al. Among authors: sinko pj. Bioconjug Chem. 2004 Nov-Dec;15(6):1322-33. doi: 10.1021/bc0498875. Bioconjug Chem. 2004. PMID: 15546199

3

Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells.

Su Y, Zhang X, Sinko PJ. Su Y, et al. Among authors: sinko pj. Mol Pharm. 2004 Jan 12;1(1):49-56. doi: 10.1021/mp0340136. Mol Pharm. 2004. PMID: 15832500

4

Quantitative assessment of the cell penetrating properties of RI-Tat-9: evidence for a cell type-specific barrier at the plasma membrane of epithelial cells.

Zhang X, Wan L, Pooyan S, Su Y, Gardner CR, Leibowitz MJ, Stein S, Sinko PJ. Zhang X, et al. Among authors: sinko pj. Mol Pharm. 2004 Mar-Apr;1(2):145-55. doi: 10.1021/mp034014y. Mol Pharm. 2004. PMID: 15832511

5

Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide.

Dharap SS, Wang Y, Chandna P, Khandare JJ, Qiu B, Gunaseelan S, Sinko PJ, Stein S, Farmanfarmaian A, Minko T. Dharap SS, et al. Among authors: sinko pj. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12962-7. doi: 10.1073/pnas.0504274102. Epub 2005 Aug 25. Proc Natl Acad Sci U S A. 2005. PMID: 16123131 Free PMC article.

6

Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects.

Wan L, Zhang X, Gunaseelan S, Pooyan S, Debrah O, Leibowitz MJ, Rabson AB, Stein S, Sinko PJ. Wan L, et al. Among authors: sinko pj. AIDS Res Ther. 2006 Apr 24;3:12. doi: 10.1186/1742-6405-3-12. AIDS Res Ther. 2006. PMID: 16635263 Free PMC article.

7

Exploitation of drug-induced Bcl-2 overexpression for restoring normal apoptosis function: a promising new approach to the treatment of multidrug resistant cancer.

Su Y, Zhang X, Sinko PJ. Su Y, et al. Among authors: sinko pj. Cancer Lett. 2007 Aug 8;253(1):115-23. doi: 10.1016/j.canlet.2007.01.018. Epub 2007 Mar 8. Cancer Lett. 2007. PMID: 17349740

8

Peritoneal macrophage uptake, pharmacokinetics and biodistribution of macrophage-targeted PEG-fMLF (N-formyl-methionyl-leucyl-phenylalanine) nanocarriers for improving HIV drug delivery.

Wan L, Pooyan S, Hu P, Leibowitz MJ, Stein S, Sinko PJ. Wan L, et al. Among authors: sinko pj. Pharm Res. 2007 Nov;24(11):2110-9. doi: 10.1007/s11095-007-9402-5. Epub 2007 Aug 15. Pharm Res. 2007. PMID: 17701325 Free PMC article.

9

Optimizing size and copy number for PEG-fMLF (N-formyl-methionyl-leucyl-phenylalanine) nanocarrier uptake by macrophages.

Wan L, Zhang X, Pooyan S, Palombo MS, Leibowitz MJ, Stein S, Sinko PJ. Wan L, et al. Among authors: sinko pj. Bioconjug Chem. 2008 Jan;19(1):28-38. doi: 10.1021/bc070066k. Epub 2007 Dec 20. Bioconjug Chem. 2008. PMID: 18092743 Free PMC article.

10

Recent trends in targeted anticancer prodrug and conjugate design.

Singh Y, Palombo M, Sinko PJ. Singh Y, et al. Among authors: sinko pj. Curr Med Chem. 2008;15(18):1802-26. doi: 10.2174/092986708785132997. Curr Med Chem. 2008. PMID: 18691040 Free PMC article. Review.

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