Linehan JL - Search Results

1

Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.

Malhotra D, Linehan JL, Dileepan T, Lee YJ, Purtha WE, Lu JV, Nelson RW, Fife BT, Orr HT, Anderson MS, Hogquist KA, Jenkins MK. Malhotra D, et al. Among authors: linehan jl. Nat Immunol. 2016 Feb;17(2):187-95. doi: 10.1038/ni.3327. Epub 2016 Jan 4. Nat Immunol. 2016. PMID: 26726812 Free PMC article.

2

Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells.

Pepper M, Linehan JL, Pagán AJ, Zell T, Dileepan T, Cleary PP, Jenkins MK. Pepper M, et al. Among authors: linehan jl. Nat Immunol. 2010 Jan;11(1):83-9. doi: 10.1038/ni.1826. Epub 2009 Nov 22. Nat Immunol. 2010. PMID: 19935657 Free PMC article.

3

CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors.

Kalekar LA, Schmiel SE, Nandiwada SL, Lam WY, Barsness LO, Zhang N, Stritesky GL, Malhotra D, Pauken KE, Linehan JL, O'Sullivan MG, Fife BT, Hogquist KA, Jenkins MK, Mueller DL. Kalekar LA, et al. Among authors: linehan jl. Nat Immunol. 2016 Mar;17(3):304-14. doi: 10.1038/ni.3331. Epub 2016 Feb 1. Nat Immunol. 2016. PMID: 26829766 Free PMC article.

4

Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

Tubo NJ, Pagán AJ, Taylor JJ, Nelson RW, Linehan JL, Ertelt JM, Huseby ES, Way SS, Jenkins MK. Tubo NJ, et al. Among authors: linehan jl. Cell. 2013 May 9;153(4):785-96. doi: 10.1016/j.cell.2013.04.007. Cell. 2013. PMID: 23663778 Free PMC article.

5

Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice.

Pauken KE, Linehan JL, Spanier JA, Sahli NL, Kalekar LA, Binstadt BA, Moon JJ, Mueller DL, Jenkins MK, Fife BT. Pauken KE, et al. Among authors: linehan jl. J Immunol. 2013 Nov 15;191(10):4913-7. doi: 10.4049/jimmunol.1301927. Epub 2013 Oct 11. J Immunol. 2013. PMID: 24123682 Free PMC article.

6

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens.

Yang Y, Torchinsky MB, Gobert M, Xiong H, Xu M, Linehan JL, Alonzo F, Ng C, Chen A, Lin X, Sczesnak A, Liao JJ, Torres VJ, Jenkins MK, Lafaille JJ, Littman DR. Yang Y, et al. Among authors: linehan jl. Nature. 2014 Jun 5;510(7503):152-6. doi: 10.1038/nature13279. Epub 2014 Apr 13. Nature. 2014. PMID: 24739972 Free PMC article.

7

Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+ dendritic cells.

Linehan JL, Dileepan T, Kashem SW, Kaplan DH, Cleary P, Jenkins MK. Linehan JL, et al. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12782-7. doi: 10.1073/pnas.1513532112. Epub 2015 Sep 28. Proc Natl Acad Sci U S A. 2015. PMID: 26417101 Free PMC article.

8

Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection.

Dileepan T, Linehan JL, Moon JJ, Pepper M, Jenkins MK, Cleary PP. Dileepan T, et al. Among authors: linehan jl. PLoS Pathog. 2011 Sep;7(9):e1002252. doi: 10.1371/journal.ppat.1002252. Epub 2011 Sep 22. PLoS Pathog. 2011. PMID: 21966268 Free PMC article.

9

BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors.

Kotov JA, Kotov DI, Linehan JL, Bardwell VJ, Gearhart MD, Jenkins MK. Kotov JA, et al. Among authors: linehan jl. J Exp Med. 2019 Jun 3;216(6):1450-1464. doi: 10.1084/jem.20182376. Epub 2019 May 3. J Exp Med. 2019. PMID: 31053612 Free PMC article.

10

Commensal-dendritic-cell interaction specifies a unique protective skin immune signature.

Naik S, Bouladoux N, Linehan JL, Han SJ, Harrison OJ, Wilhelm C, Conlan S, Himmelfarb S, Byrd AL, Deming C, Quinones M, Brenchley JM, Kong HH, Tussiwand R, Murphy KM, Merad M, Segre JA, Belkaid Y. Naik S, et al. Among authors: linehan jl. Nature. 2015 Apr 2;520(7545):104-8. doi: 10.1038/nature14052. Epub 2015 Jan 5. Nature. 2015. PMID: 25539086 Free PMC article.

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