Parker JA - Search Results

1

Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms.

Julien C, Lissouba A, Madabattula S, Fardghassemi Y, Rosenfelt C, Androschuk A, Strautman J, Wong C, Bysice A, O'sullivan J, Rouleau GA, Drapeau P, Parker JA, Bolduc FV. Julien C, et al. Among authors: parker ja. Hum Mol Genet. 2016 Mar 15;25(6):1088-99. doi: 10.1093/hmg/ddv632. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744324 Free PMC article.

2

Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.

Catoire H, Pasco MY, Abu-Baker A, Holbert S, Tourette C, Brais B, Rouleau GA, Parker JA, Néri C. Catoire H, et al. Among authors: parker ja. Hum Mol Genet. 2008 Jul 15;17(14):2108-17. doi: 10.1093/hmg/ddn109. Epub 2008 Apr 7. Hum Mol Genet. 2008. PMID: 18397876

3

Cross-talk between canonical Wnt signaling and the sirtuin-FoxO longevity pathway to protect against muscular pathology induced by mutant PABPN1 expression in C. elegans.

Pasco MY, Catoire H, Parker JA, Brais B, Rouleau GA, Néri C. Pasco MY, et al. Among authors: parker ja. Neurobiol Dis. 2010 Jun;38(3):425-33. doi: 10.1016/j.nbd.2010.03.002. Epub 2010 Mar 19. Neurobiol Dis. 2010. PMID: 20227501

4

Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis.

Catoire H, Dion PA, Xiong L, Amari M, Gaudet R, Girard SL, Noreau A, Gaspar C, Turecki G, Montplaisir JY, Parker JA, Rouleau GA. Catoire H, et al. Among authors: parker ja. Ann Neurol. 2011 Jul;70(1):170-5. doi: 10.1002/ana.22435. Epub 2011 Jun 27. Ann Neurol. 2011. PMID: 21710629

5

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.

Vaccaro A, Tauffenberger A, Aggad D, Rouleau G, Drapeau P, Parker JA. Vaccaro A, et al. Among authors: parker ja. PLoS One. 2012;7(2):e31321. doi: 10.1371/journal.pone.0031321. Epub 2012 Feb 21. PLoS One. 2012. PMID: 22363618 Free PMC article.

6

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.

Vaccaro A, Patten SA, Ciura S, Maios C, Therrien M, Drapeau P, Kabashi E, Parker JA. Vaccaro A, et al. Among authors: parker ja. PLoS One. 2012;7(7):e42117. doi: 10.1371/journal.pone.0042117. Epub 2012 Jul 27. PLoS One. 2012. PMID: 22848727 Free PMC article.

7

Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.

Tauffenberger A, Chitramuthu BP, Bateman A, Bennett HP, Parker JA. Tauffenberger A, et al. Among authors: parker ja. Hum Mol Genet. 2013 Feb 15;22(4):782-94. doi: 10.1093/hmg/dds485. Epub 2012 Nov 19. Hum Mol Genet. 2013. PMID: 23172908

8

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.

Vaccaro A, Patten SA, Aggad D, Julien C, Maios C, Kabashi E, Drapeau P, Parker JA. Vaccaro A, et al. Among authors: parker ja. Neurobiol Dis. 2013 Jul;55:64-75. doi: 10.1016/j.nbd.2013.03.015. Epub 2013 Apr 5. Neurobiol Dis. 2013. PMID: 23567652

9

Evaluation of longevity enhancing compounds against transactive response DNA-binding protein-43 neuronal toxicity.

Tauffenberger A, Julien C, Parker JA. Tauffenberger A, et al. Among authors: parker ja. Neurobiol Aging. 2013 Sep;34(9):2175-82. doi: 10.1016/j.neurobiolaging.2013.03.014. Epub 2013 Apr 13. Neurobiol Aging. 2013. PMID: 23591130

10

Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans.

Therrien M, Rouleau GA, Dion PA, Parker JA. Therrien M, et al. Among authors: parker ja. PLoS One. 2013 Dec 12;8(12):e83450. doi: 10.1371/journal.pone.0083450. eCollection 2013. PLoS One. 2013. PMID: 24349511 Free PMC article.

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