Straub SV - Search Results

1

Pharmacological characterization of the first in class clinical candidate PF-05190457: a selective ghrelin receptor competitive antagonist with inverse agonism that increases vagal afferent firing and glucose-dependent insulin secretion ex vivo.

Kong J, Chuddy J, Stock IA, Loria PM, Straub SV, Vage C, Cameron KO, Bhattacharya SK, Lapham K, McClure KF, Zhang Y, Jackson VM. Kong J, et al. Among authors: straub sv. Br J Pharmacol. 2016 May;173(9):1452-64. doi: 10.1111/bph.13439. Epub 2016 Mar 17. Br J Pharmacol. 2016. PMID: 26784385 Free PMC article.

2

Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues.

Straub SV, Perez SM, Tan B, Coughlan KA, Trebino CE, Cosgrove P, Buxton JM, Kreeger JM, Jackson VM. Straub SV, et al. Am J Physiol Endocrinol Metab. 2011 Aug;301(2):E380-90. doi: 10.1152/ajpendo.00076.2011. Epub 2011 May 17. Am J Physiol Endocrinol Metab. 2011. PMID: 21586699 Free article.

3

A spoonful of sugar helps the KV channel activity go down.

Straub SV, Nelson MT. Straub SV, et al. J Physiol. 2006 Sep 15;575(Pt 3):691. doi: 10.1113/jphysiol.2006.118091. Epub 2006 Aug 3. J Physiol. 2006. PMID: 16887870 Free PMC article. No abstract available.

4

Dynamic inositol trisphosphate-mediated calcium signals within astrocytic endfeet underlie vasodilation of cerebral arterioles.

Straub SV, Bonev AD, Wilkerson MK, Nelson MT. Straub SV, et al. J Gen Physiol. 2006 Dec;128(6):659-69. doi: 10.1085/jgp.200609650. J Gen Physiol. 2006. PMID: 17130519 Free PMC article.

5

Regulation of intracerebral arteriolar tone by K(v) channels: effects of glucose and PKC.

Straub SV, Girouard H, Doetsch PE, Hannah RM, Wilkerson MK, Nelson MT. Straub SV, et al. Am J Physiol Cell Physiol. 2009 Sep;297(3):C788-96. doi: 10.1152/ajpcell.00148.2009. Epub 2009 Jul 15. Am J Physiol Cell Physiol. 2009. PMID: 19605735 Free PMC article.

6

Local potassium signaling couples neuronal activity to vasodilation in the brain.

Filosa JA, Bonev AD, Straub SV, Meredith AL, Wilkerson MK, Aldrich RW, Nelson MT. Filosa JA, et al. Among authors: straub sv. Nat Neurosci. 2006 Nov;9(11):1397-1403. doi: 10.1038/nn1779. Nat Neurosci. 2006. PMID: 17013381

7

Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation.

Straub SV, Nelson MT. Straub SV, et al. Trends Cardiovasc Med. 2007 Aug;17(6):183-90. doi: 10.1016/j.tcm.2007.05.001. Trends Cardiovasc Med. 2007. PMID: 17662912 Free PMC article. Review.

8

Molecular coding of Kv1 channels to oppose myogenic constriction.

Straub SV, Nelson MT. Straub SV, et al. Circ Res. 2006 Jul 7;99(1):13-4. doi: 10.1161/01.RES.0000233147.38981.90. Circ Res. 2006. PMID: 16825586 Review. No abstract available.

9

Cytosolic Ca(2+) and Ca(2+)-activated Cl(-) current dynamics: insights from two functionally distinct mouse exocrine cells.

Giovannucci DR, Bruce JI, Straub SV, Arreola J, Sneyd J, Shuttleworth TJ, Yule DI. Giovannucci DR, et al. Among authors: straub sv. J Physiol. 2002 Apr 15;540(Pt 2):469-84. doi: 10.1113/jphysiol.2001.013453. J Physiol. 2002. PMID: 11956337 Free PMC article.

10

Calcium wave propagation in pancreatic acinar cells: functional interaction of inositol 1,4,5-trisphosphate receptors, ryanodine receptors, and mitochondria.

Straub SV, Giovannucci DR, Yule DI. Straub SV, et al. J Gen Physiol. 2000 Oct;116(4):547-60. doi: 10.1085/jgp.116.4.547. J Gen Physiol. 2000. PMID: 11004204 Free PMC article.

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