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Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension.
Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel T, Wenzel P. Kossmann S, et al. Among authors: jackel s. Sci Transl Med. 2017 Feb 1;9(375):eaah4923. doi: 10.1126/scitranslmed.aah4923. Sci Transl Med. 2017. PMID: 28148841
Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.
Kiouptsi K, Grill A, Mann A, Döhrmann M, Lillich M, Jäckel S, Malinarich F, Formes H, Manukyan D, Subramaniam S, Khandagale A, Karwot C, Thal SC, Bosmann M, Scharrer I, Jurk K, Reinhardt C. Kiouptsi K, et al. Among authors: jackel s. PLoS One. 2017 Aug 24;12(8):e0183590. doi: 10.1371/journal.pone.0183590. eCollection 2017. PLoS One. 2017. PMID: 28837614 Free PMC article.
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice.
Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. Kiouptsi K, et al. Among authors: jackel s. mBio. 2019 Oct 22;10(5):e02298-19. doi: 10.1128/mBio.02298-19. mBio. 2019. PMID: 31641089 Free PMC article.
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice.
Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, Schubert I, Hoseinpour P, Chandraratne S, von Brühl ML, Gaertner F, Lorenz M, Agresti A, Coletti R, Antoine DJ, Heermann R, Jung K, Reese S, Laitinen I, Schwaiger M, Walch A, Sperandio M, Nawroth PP, Reinhardt C, Jäckel S, Bianchi ME, Massberg S. Stark K, et al. Among authors: jackel s. Blood. 2016 Nov 17;128(20):2435-2449. doi: 10.1182/blood-2016-04-710632. Epub 2016 Aug 29. Blood. 2016. PMID: 27574188 Free PMC article.
73 results