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Page 1
Serial femtosecond X-ray diffraction of enveloped virus microcrystals.
Lawrence RM, Conrad CE, Zatsepin NA, Grant TD, Liu H, James D, Nelson G, Subramanian G, Aquila A, Hunter MS, Liang M, Boutet S, Coe J, Spence JC, Weierstall U, Liu W, Fromme P, Cherezov V, Hogue BG. Lawrence RM, et al. Struct Dyn. 2015 Aug 20;2(4):041720. doi: 10.1063/1.4929410. eCollection 2015 Jul. Struct Dyn. 2015. PMID: 26798819 Free PMC article.
Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1.
Lee HH, Cherni I, Yu H, Fromme R, Doran JD, Grotjohann I, Mittman M, Basu S, Deb A, Dörner K, Aquila A, Barty A, Boutet S, Chapman HN, Doak RB, Hunter MS, James D, Kirian RA, Kupitz C, Lawrence RM, Liu H, Nass K, Schlichting I, Schmidt KE, Seibert MM, Shoeman RL, Spence JC, Stellato F, Weierstall U, Williams GJ, Yoon C, Wang D, Zatsepin NA, Hogue BG, Matoba N, Fromme P, Mor TS. Lee HH, et al. Among authors: lawrence rm. IUCrJ. 2014 Aug 20;1(Pt 5):305-17. doi: 10.1107/S2052252514014900. eCollection 2014 Sep 1. IUCrJ. 2014. PMID: 25295172 Free PMC article.
Diffraction data of core-shell nanoparticles from an X-ray free electron laser.
Li X, Chiu CY, Wang HJ, Kassemeyer S, Botha S, Shoeman RL, Lawrence RM, Kupitz C, Kirian R, James D, Wang D, Nelson G, Messerschmidt M, Boutet S, Williams GJ, Hartmann E, Jafarpour A, Foucar LM, Barty A, Chapman H, Liang M, Menzel A, Wang F, Basu S, Fromme R, Doak RB, Fromme P, Weierstall U, Huang MH, Spence JC, Schlichting I, Hogue BG, Liu H. Li X, et al. Among authors: lawrence rm. Sci Data. 2017 Apr 11;4:170048. doi: 10.1038/sdata.2017.48. Sci Data. 2017. PMID: 28398334 Free PMC article.
Corrigendum: Diffraction data of core-shell nanoparticles from an X-ray free electron laser.
Li X, Chiu CY, Wang HJ, Kassemeyer S, Botha S, Shoeman RL, Lawrence RM, Kupitz C, Kirian R, James D, Wang D, Nelson G, Messerschmidt M, Boutet S, Williams GJ, Hartmann E, Jafarpour A, Foucar LM, Barty A, Chapman H, Liang M, Menzel A, Wang F, Basu S, Fromme R, Doak RB, Fromme P, Weierstall U, Huang MH, Spence JCH, Schlichting I, Hogue BG, Liu H. Li X, et al. Among authors: lawrence rm. Sci Data. 2017 Oct 24;4:170154. doi: 10.1038/sdata.2017.154. Sci Data. 2017. PMID: 29064473 Free PMC article.
Transmission electron microscopy for the evaluation and optimization of crystal growth.
Stevenson HP, Lin G, Barnes CO, Sutkeviciute I, Krzysiak T, Weiss SC, Reynolds S, Wu Y, Nagarajan V, Makhov AM, Lawrence R, Lamm E, Clark L, Gardella TJ, Hogue BG, Ogata CM, Ahn J, Gronenborn AM, Conway JF, Vilardaga JP, Cohen AE, Calero G. Stevenson HP, et al. Acta Crystallogr D Struct Biol. 2016 May;72(Pt 5):603-15. doi: 10.1107/S2059798316001546. Epub 2016 Apr 26. Acta Crystallogr D Struct Biol. 2016. PMID: 27139624 Free PMC article.
Discovery of Potent and Selective Quinoxaline-Based Protease-Activated Receptor 4 (PAR4) Antagonists for the Prevention of Arterial Thrombosis.
Zhang X, Jiang W, Richter JM, Bates JA, Reznik SK, Stachura S, Rampulla R, Doddalingappa D, Ulaganathan S, Hua J, Bostwick JS, Sum C, Posy S, Malmstrom S, Dickey J, Harden D, Lawrence RM, Guarino VR, Schumacher WA, Wong P, Yang J, Gordon DA, Wexler RR, Priestley ES. Zhang X, et al. Among authors: lawrence rm. J Med Chem. 2024 Mar 14;67(5):3571-3589. doi: 10.1021/acs.jmedchem.3c01986. Epub 2024 Feb 22. J Med Chem. 2024. PMID: 38385264
MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity.
Cheng D, Zinker BA, Luo Y, Shipkova P, De Oliveira CH, Krishna G, Brown EA, Boehm SL, Tirucherai GS, Gu H, Ma Z, Chu CH, Onorato JM, Kopcho LM, Ammar R, Smith J, Devasthale P, Lawrence RM, Stryker SA, Dierks EA, Azzara AV, Carayannopoulos L, Charles ED, Lentz KA, Gordon DA. Cheng D, et al. Among authors: lawrence rm. Cell Metab. 2022 Nov 1;34(11):1732-1748.e5. doi: 10.1016/j.cmet.2022.10.007. Cell Metab. 2022. PMID: 36323235 Free article.
147 results