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17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.
Stout MB, Steyn FJ, Jurczak MJ, Camporez JG, Zhu Y, Hawse JR, Jurk D, Palmer AK, Xu M, Pirtskhalava T, Evans GL, de Souza Santos R, Frank AP, White TA, Monroe DG, Singh RJ, Casaclang-Verzosa G, Miller JD, Clegg DJ, LeBrasseur NK, von Zglinicki T, Shulman GI, Tchkonia T, Kirkland JL. Stout MB, et al. Among authors: shulman gi. J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):3-15. doi: 10.1093/gerona/glv309. Epub 2016 Jan 24. J Gerontol A Biol Sci Med Sci. 2017. PMID: 26809497 Free PMC article.
The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.
Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D, Dong J, Zhang D, Jurczak MJ, Löffler MG, Cresswell J, Yu XX, Murray SF, Bhanot S, Monia BP, Bogan JS, Samuel V, Shulman GI. Nagai Y, et al. Among authors: shulman gi. Cell Metab. 2009 Mar;9(3):252-64. doi: 10.1016/j.cmet.2009.01.011. Cell Metab. 2009. PMID: 19254570 Free PMC article.
A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain.
Jornayvaz FR, Jurczak MJ, Lee HY, Birkenfeld AL, Frederick DW, Zhang D, Zhang XM, Samuel VT, Shulman GI. Jornayvaz FR, et al. Among authors: shulman gi. Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E808-15. doi: 10.1152/ajpendo.00361.2010. Epub 2010 Aug 31. Am J Physiol Endocrinol Metab. 2010. PMID: 20807839 Free PMC article.
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.
Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI. Lee HY, et al. Among authors: shulman gi. Cell Metab. 2010 Dec 1;12(6):668-74. doi: 10.1016/j.cmet.2010.11.004. Cell Metab. 2010. PMID: 21109199 Free PMC article.
Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance.
Lee HY, Birkenfeld AL, Jornayvaz FR, Jurczak MJ, Kanda S, Popov V, Frederick DW, Zhang D, Guigni B, Bharadwaj KG, Choi CS, Goldberg IJ, Park JH, Petersen KF, Samuel VT, Shulman GI. Lee HY, et al. Among authors: shulman gi. Hepatology. 2011 Nov;54(5):1650-60. doi: 10.1002/hep.24571. Epub 2011 Aug 19. Hepatology. 2011. PMID: 21793029 Free PMC article.
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.
Birkenfeld AL, Lee HY, Guebre-Egziabher F, Alves TC, Jurczak MJ, Jornayvaz FR, Zhang D, Hsiao JJ, Martin-Montalvo A, Fischer-Rosinsky A, Spranger J, Pfeiffer AF, Jordan J, Fromm MF, König J, Lieske S, Carmean CM, Frederick DW, Weismann D, Knauf F, Irusta PM, De Cabo R, Helfand SL, Samuel VT, Shulman GI. Birkenfeld AL, et al. Among authors: shulman gi. Cell Metab. 2011 Aug 3;14(2):184-95. doi: 10.1016/j.cmet.2011.06.009. Cell Metab. 2011. PMID: 21803289 Free PMC article.
Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism.
Birkenfeld AL, Lee HY, Majumdar S, Jurczak MJ, Camporez JP, Jornayvaz FR, Frederick DW, Guigni B, Kahn M, Zhang D, Weismann D, Arafat AM, Pfeiffer AF, Lieske S, Oyadomari S, Ron D, Samuel VT, Shulman GI. Birkenfeld AL, et al. Among authors: shulman gi. J Biol Chem. 2011 Oct 21;286(42):36163-70. doi: 10.1074/jbc.M111.228817. Epub 2011 Aug 5. J Biol Chem. 2011. PMID: 21832042 Free PMC article.
599 results