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Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.
Lin NY, Distler A, Beyer C, Philipi-Schöbinger A, Breda S, Dees C, Stock M, Tomcik M, Niemeier A, Dell'Accio F, Gelse K, Mattson MP, Schett G, Distler JH. Lin NY, et al. Among authors: niemeier a. Ann Rheum Dis. 2016 Nov;75(11):2037-2044. doi: 10.1136/annrheumdis-2015-208420. Epub 2016 Feb 5. Ann Rheum Dis. 2016. PMID: 26851274
Signature of circulating microRNAs in osteoarthritis.
Beyer C, Zampetaki A, Lin NY, Kleyer A, Perricone C, Iagnocco A, Distler A, Langley SR, Gelse K, Sesselmann S, Lorenzini R, Niemeier A, Swoboda B, Distler JH, Santer P, Egger G, Willeit J, Mayr M, Schett G, Kiechl S. Beyer C, et al. Among authors: niemeier a. Ann Rheum Dis. 2015 Mar;74(3):e18. doi: 10.1136/annrheumdis-2013-204698. Epub 2014 Feb 10. Ann Rheum Dis. 2015. PMID: 24515954
Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo.
Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J, Pitzalis C, Perretti M, Dell'Accio F. Eldridge S, et al. Among authors: niemeier a. Ann Rheum Dis. 2016 Jun;75(6):1228-35. doi: 10.1136/annrheumdis-2015-207316. Epub 2015 Aug 19. Ann Rheum Dis. 2016. PMID: 26290588 Free PMC article.
Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin.
Andreev D, Liu M, Weidner D, Kachler K, Faas M, Grüneboom A, Schlötzer-Schrehardt U, Muñoz LE, Steffen U, Grötsch B, Killy B, Krönke G, Luebke AM, Niemeier A, Wehrhan F, Lang R, Schett G, Bozec A. Andreev D, et al. Among authors: niemeier a. J Clin Invest. 2020 Sep 1;130(9):4811-4830. doi: 10.1172/JCI134214. J Clin Invest. 2020. PMID: 32773408 Free PMC article.
Increased bone formation in mice lacking apolipoprotein E.
Schilling AF, Schinke T, Münch C, Gebauer M, Niemeier A, Priemel M, Streichert T, Rueger JM, Amling M. Schilling AF, et al. Among authors: niemeier a. J Bone Miner Res. 2005 Feb;20(2):274-82. doi: 10.1359/JBMR.041101. Epub 2004 Nov 1. J Bone Miner Res. 2005. PMID: 15647822 Free article.
Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder.
Hawellek T, Hubert J, Hischke S, Krause M, Bertrand J, Pap T, Püschel K, Rüther W, Niemeier A. Hawellek T, et al. Among authors: niemeier a. Osteoarthritis Cartilage. 2016 Dec;24(12):2092-2099. doi: 10.1016/j.joca.2016.06.020. Epub 2016 Jul 5. Osteoarthritis Cartilage. 2016. PMID: 27390030 Free article.
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