Rettenmaier TJ - Search Results

1

CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites.

Cimermancic P, Weinkam P, Rettenmaier TJ, Bichmann L, Keedy DA, Woldeyes RA, Schneidman-Duhovny D, Demerdash ON, Mitchell JC, Wells JA, Fraser JS, Sali A. Cimermancic P, et al. Among authors: rettenmaier tj. J Mol Biol. 2016 Feb 22;428(4):709-719. doi: 10.1016/j.jmb.2016.01.029. Epub 2016 Feb 5. J Mol Biol. 2016. PMID: 26854760 Free PMC article.

2

FP Tethering: a screening technique to rapidly identify compounds that disrupt protein-protein interactions.

Lodge JM, Rettenmaier TJ, Wells JA, Pomerantz WC, Mapp AK. Lodge JM, et al. Among authors: rettenmaier tj. Medchemcomm. 2014 Mar 1;5:370-375. doi: 10.1039/C3MD00356F. Medchemcomm. 2014. PMID: 24795804 Free PMC article.

3

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.

Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA. Rettenmaier TJ, et al. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18590-5. doi: 10.1073/pnas.1415365112. Epub 2014 Dec 17. Proc Natl Acad Sci U S A. 2014. PMID: 25518860 Free PMC article.

4

Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking.

Rettenmaier TJ, Fan H, Karpiak J, Doak A, Sali A, Shoichet BK, Wells JA. Rettenmaier TJ, et al. J Med Chem. 2015 Oct 22;58(20):8285-8291. doi: 10.1021/acs.jmedchem.5b01216. Epub 2015 Oct 12. J Med Chem. 2015. PMID: 26443011 Free PMC article.

5

Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues.

Seaman JE, Julien O, Lee PS, Rettenmaier TJ, Thomsen ND, Wells JA. Seaman JE, et al. Among authors: rettenmaier tj. Cell Death Differ. 2016 Oct;23(10):1717-26. doi: 10.1038/cdd.2016.62. Epub 2016 Jul 1. Cell Death Differ. 2016. PMID: 27367566 Free PMC article.

6

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.

Keedy DA, Hill ZB, Biel JT, Kang E, Rettenmaier TJ, Brandão-Neto J, Pearce NM, von Delft F, Wells JA, Fraser JS. Keedy DA, et al. Among authors: rettenmaier tj. Elife. 2018 Jun 7;7:e36307. doi: 10.7554/eLife.36307. Elife. 2018. PMID: 29877794 Free PMC article.

7

Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.

Harvey EP, Hauseman ZJ, Cohen DT, Rettenmaier TJ, Lee S, Huhn AJ, Wales TE, Seo HS, Luccarelli J, Newman CE, Guerra RM, Bird GH, Dhe-Paganon S, Engen JR, Wells JA, Walensky LD. Harvey EP, et al. Among authors: rettenmaier tj. Cell Chem Biol. 2020 Jun 18;27(6):647-656.e6. doi: 10.1016/j.chembiol.2020.04.004. Epub 2020 May 14. Cell Chem Biol. 2020. PMID: 32413285 Free PMC article.

8

Redox priming promotes Aurora A activation during mitosis.

Lim DC, Joukov V, Rettenmaier TJ, Kumagai A, Dunphy WG, Wells JA, Yaffe MB. Lim DC, et al. Among authors: rettenmaier tj. Sci Signal. 2020 Jul 21;13(641):eabb6707. doi: 10.1126/scisignal.abb6707. Sci Signal. 2020. PMID: 32694171 Free PMC article.

9

Covalent inhibition of pro-apoptotic BAX.

McHenry MW, Shi P, Camara CM, Cohen DT, Rettenmaier TJ, Adhikary U, Gygi MA, Yang K, Gygi SP, Wales TE, Engen JR, Wells JA, Walensky LD. McHenry MW, et al. Among authors: rettenmaier tj. Nat Chem Biol. 2024 Aug;20(8):1022-1032. doi: 10.1038/s41589-023-01537-6. Epub 2024 Jan 17. Nat Chem Biol. 2024. PMID: 38233584

10

Hydride as a leaving group in the reaction of pinacolborane with halides under ambient Grignard and Barbier conditions. One-pot synthesis of alkyl, aryl, heteroaryl, vinyl, and allyl pinacolboronic esters.

Clary JW, Rettenmaier TJ, Snelling R, Bryks W, Banwell J, Wipke WT, Singaram B. Clary JW, et al. Among authors: rettenmaier tj. J Org Chem. 2011 Dec 2;76(23):9602-10. doi: 10.1021/jo201093u. Epub 2011 Nov 1. J Org Chem. 2011. PMID: 22040316

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