Characterization of (R)-2-hydroxyisocaproate dehydrogenase and a family III coenzyme A transferase involved in reduction of L-leucine to isocaproate by Clostridium difficile.
Kim J, Darley D, Selmer T, Buckel W.
Kim J, et al. Among authors: buckel w.
Appl Environ Microbiol. 2006 Sep;72(9):6062-9. doi: 10.1128/AEM.00772-06.
Appl Environ Microbiol. 2006.
PMID: 16957230
Free PMC article.
The dehydratase requires activation by an ATP-dependent one-electron transfer (J. Kim, D. Darley, and W. Buckel, FEBS J. 272:550-561, 2005). Prior to the dehydration, a dehydrogenase and a CoA transferase are supposed to be involved in the formation of (R)-2-hydroxy …
The dehydratase requires activation by an ATP-dependent one-electron transfer (J. Kim, D. Darley, and W. Buckel, FEBS J. 272:5 …