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Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice.
Chen P, Torralba M, Tan J, Embree M, Zengler K, Stärkel P, van Pijkeren JP, DePew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B. Chen P, et al. Gastroenterology. 2015 Jan;148(1):203-214.e16. doi: 10.1053/j.gastro.2014.09.014. Epub 2014 Sep 16. Gastroenterology. 2015. PMID: 25239591 Free PMC article.
Intestinal fungi contribute to development of alcoholic liver disease.
Yang AM, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, Bluemel S, Hartmann P, Xu J, Koyama Y, Kisseleva T, Torralba MG, Moncera K, Beeri K, Chen CS, Freese K, Hellerbrand C, Lee SM, Hoffman HM, Mehal WZ, Garcia-Tsao G, Mutlu EA, Keshavarzian A, Brown GD, Ho SB, Bataller R, Stärkel P, Fouts DE, Schnabl B. Yang AM, et al. Among authors: chen cs, chen p. J Clin Invest. 2017 Jun 30;127(7):2829-2841. doi: 10.1172/JCI90562. Epub 2017 May 22. J Clin Invest. 2017. PMID: 28530644 Free PMC article.
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice.
Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, Rossi SJ, DePaoli AM, Downes M, Evans RM, Brenner DA, Schnabl B. Hartmann P, et al. Among authors: chen p. Hepatology. 2018 Jun;67(6):2150-2166. doi: 10.1002/hep.29676. Epub 2018 Apr 16. Hepatology. 2018. PMID: 29159825 Free PMC article.
Microbiota and Alcoholic Liver Disease.
Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. Chen P, et al. Alcohol Clin Exp Res. 2016 Aug;40(8):1791-2. doi: 10.1111/acer.13129. Epub 2016 Jul 1. Alcohol Clin Exp Res. 2016. PMID: 27364225 No abstract available.
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