Wyllie DJA - Search Results

1

Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition.

Rzechorzek NM, Connick P, Livesey MR, Borooah S, Patani R, Burr K, Story D, Wyllie DJA, Hardingham GE, Chandran S. Rzechorzek NM, et al. Among authors: wyllie dja. EBioMedicine. 2015 Dec 12;3:141-154. doi: 10.1016/j.ebiom.2015.12.010. eCollection 2016 Jan. EBioMedicine. 2015. PMID: 26870825 Free PMC article.

2

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.

Chen PE, Geballe MT, Katz E, Erreger K, Livesey MR, O'Toole KK, Le P, Lee CJ, Snyder JP, Traynelis SF, Wyllie DJ. Chen PE, et al. J Physiol. 2008 Jan 1;586(1):227-45. doi: 10.1113/jphysiol.2007.143172. Epub 2007 Oct 25. J Physiol. 2008. PMID: 17962328 Free PMC article.

3

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.

Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Papadia S, et al. Nat Neurosci. 2008 Apr;11(4):476-87. doi: 10.1038/nn2071. Epub 2008 Mar 23. Nat Neurosci. 2008. PMID: 18344994 Free PMC article.

4

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death.

Martel MA, Wyllie DJ, Hardingham GE. Martel MA, et al. Neuroscience. 2009 Jan 12;158(1):334-43. doi: 10.1016/j.neuroscience.2008.01.080. Epub 2008 Mar 4. Neuroscience. 2009. PMID: 18378405 Free PMC article.

5

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand.

Soriano FX, Martel MA, Papadia S, Vaslin A, Baxter P, Rickman C, Forder J, Tymianski M, Duncan R, Aarts M, Clarke P, Wyllie DJ, Hardingham GE. Soriano FX, et al. J Neurosci. 2008 Oct 15;28(42):10696-710. doi: 10.1523/JNEUROSCI.1207-08.2008. J Neurosci. 2008. PMID: 18923045 Free PMC article.

6

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression.

Martel MA, Soriano FX, Baxter P, Rickman C, Duncan R, Wyllie DJ, Hardingham GE. Martel MA, et al. Channels (Austin). 2009 Jan-Feb;3(1):12-5. doi: 10.4161/chan.3.1.7864. Epub 2009 Jan 16. Channels (Austin). 2009. PMID: 19221512 Free article.

7

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

Patani R, Compston A, Puddifoot CA, Wyllie DJ, Hardingham GE, Allen ND, Chandran S. Patani R, et al. PLoS One. 2009 Oct 6;4(10):e7327. doi: 10.1371/journal.pone.0007327. PLoS One. 2009. PMID: 19806200 Free PMC article.

8

Suppression of the intrinsic apoptosis pathway by synaptic activity.

Léveillé F, Papadia S, Fricker M, Bell KF, Soriano FX, Martel MA, Puddifoot C, Habel M, Wyllie DJ, Ikonomidou C, Tolkovsky AM, Hardingham GE. Léveillé F, et al. J Neurosci. 2010 Feb 17;30(7):2623-35. doi: 10.1523/JNEUROSCI.5115-09.2010. J Neurosci. 2010. PMID: 20164347 Free PMC article.

9

Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.

Hardingham GE, Patani R, Baxter P, Wyllie DJ, Chandran S. Hardingham GE, et al. Mol Neurobiol. 2010 Aug;42(1):97-102. doi: 10.1007/s12035-010-8136-2. Epub 2010 Apr 30. Mol Neurobiol. 2010. PMID: 20431962 Free PMC article.

10

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.

Patani R, Hollins AJ, Wishart TM, Puddifoot CA, Alvarez S, de Lera AR, Wyllie DJ, Compston DA, Pedersen RA, Gillingwater TH, Hardingham GE, Allen ND, Chandran S. Patani R, et al. Nat Commun. 2011;2:214. doi: 10.1038/ncomms1216. Nat Commun. 2011. PMID: 21364553 Free PMC article.

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